Arachidonoyl-glycerol (2-AG) and arachidonyl-ethanolamide (AEA) are endocannabinoids
that have been implicated in many physiologic disorders, including obesity, metabolic …

Inflammatory bowel disease (IBD) is a general term used to describe a group of chronic
inflammatory conditions of the gastrointestinal tract of unknown etiology, including two …

Objective The technology for the growth of human intestinal epithelial cells is rapidly
progressing. An exciting possibility is that this system could serve as a platform for …

Notwithstanding the ongoing debate on their full potential in health and disease, there is
general consensus that n-3 PUFAs play important physiological roles. Increasing dietary n-3 …

Cannabis sativa and its extracts have been used for centuries, both medicinally and
recreationally. There is accumulating evidence that exogenous cannabis and related …

Background Clinical trials investigating the use of cannabinoid drugs for the treatment of
intestinal inflammation are anticipated secondary to preclinical literature demonstrating …

The endocannabinoid system has previously been shown to play a role in the permeability
and inflammatory response of the human gut. The goal of our study was to determine the …

Purinergic receptors play an important role in inflammation, and can be activated by ATP
released via pannexin channels and/or connexin hemichannels. The purinergic P2X7 …

Introduction: The pannexin-1 (Panx1) channels are found in many cell types, and ATP
released from these channels can act on nearby cells activating purinergic P2X7 receptors …

Emerging evidence confirms beneficial properties of probiotics in promoting growth and
immunity of farmed chicken. However, the molecular mechanisms underlying the host …