Traumatic brain injury and risk of neurodegenerative disorder
Traumatic brain injury (TBI), particularly of greater severity (ie, moderate to severe), has
been identified as a risk factor for all-cause dementia and Parkinson's disease, with risk for …
been identified as a risk factor for all-cause dementia and Parkinson's disease, with risk for …
Traumatic brain injury: neuropathological, neurocognitive and neurobehavioral sequelae
Traumatic brain injury (TBI) causes substantial neurological disabilities and mental distress.
Annual TBI incidence is in magnitude of millions, making it a global health challenge …
Annual TBI incidence is in magnitude of millions, making it a global health challenge …
A survey of human gait-based artificial intelligence applications
We performed an electronic database search of published works from 2012 to mid-2021 that
focus on human gait studies and apply machine learning techniques. We identified six key …
focus on human gait studies and apply machine learning techniques. We identified six key …
Questions concerning the role of amyloid-β in the definition, aetiology and diagnosis of Alzheimer's disease
The dominant hypothesis of Alzheimer's disease (AD) aetiology, the neuropathological
guidelines for diagnosing AD and the majority of high-profile therapeutic efforts, in both …
guidelines for diagnosing AD and the majority of high-profile therapeutic efforts, in both …
Post-acute blood biomarkers and disease progression in traumatic brain injury
There is substantial interest in the potential for traumatic brain injury to result in progressive
neurological deterioration. While blood biomarkers such as glial fibrillary acid protein …
neurological deterioration. While blood biomarkers such as glial fibrillary acid protein …
How the immune system shapes neurodegenerative diseases
Neurodegenerative diseases are a major cause of death and disability worldwide and are
influenced by many factors including age, genetics, and injuries. While these diseases are …
influenced by many factors including age, genetics, and injuries. While these diseases are …
The oral-gut-brain AXIS: the influence of microbes in Alzheimer's disease
Narengaowa, W Kong, F Lan, UF Awan… - Frontiers in cellular …, 2021 - frontiersin.org
Alzheimer's disease (AD) is one of the most frequently diagnosed neurodegenerative
disorders worldwide and poses a major challenge for both affected individuals and their …
disorders worldwide and poses a major challenge for both affected individuals and their …
Lentivirus-mediated downregulation of α-synuclein reduces neuroinflammation and promotes functional recovery in rats with spinal cord injury
H Zeng, N Liu, Y Yang, H **ng, X Liu, F Li, G La… - Journal of …, 2019 - Springer
Background The prognosis of spinal cord injury (SCI) is closely related to secondary injury,
which is dominated by neuroinflammation. There is evidence that α-synuclein aggregates …
which is dominated by neuroinflammation. There is evidence that α-synuclein aggregates …
TDP-43 and inflammation: implications for amyotrophic lateral sclerosis and frontotemporal dementia
The abnormal mislocalisation and ubiquitinated protein aggregation of the TAR DNA
binding protein 43 (TDP-43) within the cytoplasm of neurons and glia in the central nervous …
binding protein 43 (TDP-43) within the cytoplasm of neurons and glia in the central nervous …
Tau immunophenotypes in chronic traumatic encephalopathy recapitulate those of ageing and Alzheimer's disease
Traumatic brain injury (TBI) is a risk factor for neurodegenerative disease, including chronic
traumatic encephalopathy (CTE). Preliminary consensus criteria define the pathognomonic …
traumatic encephalopathy (CTE). Preliminary consensus criteria define the pathognomonic …