Advantages of integrating Brillouin microscopy in multimodal mechanical map** of cells and tissues
Recent research has highlighted the growing significance of the mechanical properties of
cells and tissues in the proper execution of physiological functions within an organism; …
cells and tissues in the proper execution of physiological functions within an organism; …
Molecular Force Sensors for Biological Application
The mechanical forces exerted by cells on their surrounding microenvironment are known
as cellular traction forces. These forces play crucial roles in various biological processes …
as cellular traction forces. These forces play crucial roles in various biological processes …
Micro-tensile rheology of fibrous gels quantifies strain-dependent anisotropy
Semiflexible fiber gels such as collagen and fibrin have unique nonlinear mechanical
properties that play an important role in tissue morphogenesis, wound healing, and cancer …
properties that play an important role in tissue morphogenesis, wound healing, and cancer …
EMT-related cell-matrix interactions are linked to states of cell unjamming in cancer spheroid invasion
Epithelial-to-mesenchymal transitions (EMT) and unjamming transitions provide two distinct
pathways for cancer cells to become invasive, but it is still unclear to what extent these …
pathways for cancer cells to become invasive, but it is still unclear to what extent these …
Enhancing PKA-dependent mesothelial barrier integrity reduces ovarian cancer transmesothelial migration via inhibition of contractility
Cancer-mesothelial cell interactions are critical for multiple solid tumors to colonize the
surface of peritoneal organs. Understanding mechanisms of mesothelial barrier dysfunction …
surface of peritoneal organs. Understanding mechanisms of mesothelial barrier dysfunction …
EMT-dependent cell-matrix interactions are linked to unjamming transitions in cancer spheroid invasion
A van der Net, Z Rahman, AD Bordoloi, I Muntz… - bioRxiv, 2024 - biorxiv.org
The plasticity of cancer cells allows them to switch between different migration modes,
promoting their invasion into the extracellular matrix (ECM) and hence increasing the risks of …
promoting their invasion into the extracellular matrix (ECM) and hence increasing the risks of …
Linking Molecular Tension and Cellular Tractions: A Multiscale Approach to Focal Adhesion Mechanics
Focal adhesions (FAs) are mechanosensitive structures that mediate force transmission
between cells and the extracellular matrix. While Traction Force Microscopy (TFM) quantifies …
between cells and the extracellular matrix. While Traction Force Microscopy (TFM) quantifies …
Mesothelial Barrier Dysfunction in Ovarian Cancer Metastasis
DE Jazwinska - 2024 - d-scholarship.pitt.edu
Ovarian cancer is the leading cause of death among all gynecological cancers, with most
patients being diagnosed with metastatic disease. For metastatic implants to form …
patients being diagnosed with metastatic disease. For metastatic implants to form …