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[HTML][HTML] Natural compounds and products from an anti-aging perspective
G Bjørklund, M Shanaida, R Lysiuk, M Butnariu… - Molecules, 2022 - mdpi.com
Aging is a very complex process that is accompanied by a degenerative impairment in many
of the major functions of the human body over time. This inevitable process is influenced by …
of the major functions of the human body over time. This inevitable process is influenced by …
Nutritional components in Western diet versus Mediterranean diet at the gut microbiota–immune system interplay. Implications for health and disease
C García-Montero, O Fraile-Martínez… - Nutrients, 2021 - mdpi.com
The most prevalent diseases of our time, non-communicable diseases (NCDs)(including
obesity, type 2 diabetes, cardiovascular diseases and some types of cancer) are rising …
obesity, type 2 diabetes, cardiovascular diseases and some types of cancer) are rising …
Reprogramming of fatty acid metabolism in cancer
N Koundouros, G Poulogiannis - British journal of cancer, 2020 - nature.com
A common feature of cancer cells is their ability to rewire their metabolism to sustain the
production of ATP and macromolecules needed for cell growth, division and survival. In …
production of ATP and macromolecules needed for cell growth, division and survival. In …
Overconsumption of Omega‐6 polyunsaturated fatty acids (PUFAs) versus deficiency of Omega‐3 PUFAs in modern‐day diets: the disturbing factor for their “balanced …
AH Mariamenatu, EM Abdu - Journal of lipids, 2021 - Wiley Online Library
Polyunsaturated fatty acids (PUFAs) contain≥ 2 double‐bond desaturations within the acyl
chain. Omega‐3 (n‐3) and Omega‐6 (n‐6) PUFAs are the two known important families in …
chain. Omega‐3 (n‐3) and Omega‐6 (n‐6) PUFAs are the two known important families in …
[HTML][HTML] Natural products in drug discovery: advances and opportunities
AG Atanasov, SB Zotchev, VM Dirsch… - Nature reviews Drug …, 2021 - nature.com
Natural products and their structural analogues have historically made a major contribution
to pharmacotherapy, especially for cancer and infectious diseases. Nevertheless, natural …
to pharmacotherapy, especially for cancer and infectious diseases. Nevertheless, natural …
Leaky gut: effect of dietary fiber and fats on microbiome and intestinal barrier
H Usuda, T Okamoto, K Wada - International journal of molecular …, 2021 - mdpi.com
Intestinal tract is the boundary that prevents harmful molecules from invading into the
mucosal tissue, followed by systemic circulation. Intestinal permeability is an index for …
mucosal tissue, followed by systemic circulation. Intestinal permeability is an index for …
Associations among dietary omega‐3 polyunsaturated fatty acids, the gut microbiota, and intestinal immunity
Y Fu, Y Wang, H Gao, DH Li, RR Jiang… - Mediators of …, 2021 - Wiley Online Library
Omega‐3 polyunsaturated fatty acids (omega‐3 PUFAs), which are essential fatty acids that
humans should obtain from diet, have potential benefits for human health. In addition to …
humans should obtain from diet, have potential benefits for human health. In addition to …
Intestinal barrier and permeability in health, obesity and NAFLD
P Portincasa, L Bonfrate, M Khalil, MD Angelis… - Biomedicines, 2021 - mdpi.com
The largest surface of the human body exposed to the external environment is the gut. At this
level, the intestinal barrier includes luminal microbes, the mucin layer, gastrointestinal …
level, the intestinal barrier includes luminal microbes, the mucin layer, gastrointestinal …
[HTML][HTML] Dietary habits and nutrition in rheumatoid arthritis: can diet influence disease development and clinical manifestations?
C Gioia, B Lucchino, MG Tarsitano, C Iannuccelli… - Nutrients, 2020 - mdpi.com
Rheumatoid arthritis (RA) is a systemic, autoimmune disease characterized by joint
involvement, with progressive cartilage and bone destruction. Genetic and environmental …
involvement, with progressive cartilage and bone destruction. Genetic and environmental …
Effects of dietary fat on gut microbiota and faecal metabolites, and their relationship with cardiometabolic risk factors: a 6-month randomised controlled-feeding trial
Objective to investigate whether diets differing in fat content alter the gut microbiota and
faecal metabolomic profiles, and to determine their relationship with cardiometabolic risk …
faecal metabolomic profiles, and to determine their relationship with cardiometabolic risk …