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B7-H3 in brain malignancies: immunology and immunotherapy
X Guo, M Chang, Y Wang, B ** such treatments for solid tumors, including brain tumors …
[HTML][HTML] Hopes on immunotherapy targeting B7-H3 in neuroblastoma
R Pulido, CE Nunes-Xavier - Translational Oncology, 2023 - Elsevier
Neuroblastoma is one of the most aggressive cancer forms in children, with highly
heterogenous clinical manifestations ranging from spontaneous regression to high …
heterogenous clinical manifestations ranging from spontaneous regression to high …
Targeting B7-H3—A Novel Strategy for the Design of Anticancer Agents for Extracranial Pediatric Solid Tumors Treatment
P Rasic, M Jeremic, R Jeremic, M Dusanovic Pjevic… - Molecules, 2023 - mdpi.com
Recent scientific data recognize the B7-H3 checkpoint molecule as a potential target for
immunotherapy of pediatric solid tumors (PSTs). B7-H3 is highly expressed in extracranial …
immunotherapy of pediatric solid tumors (PSTs). B7-H3 is highly expressed in extracranial …
Intracerebroventricular B7-H3-targeting CAR T cells for diffuse intrinsic pontine glioma: a phase 1 trial
NA Vitanza, R Ronsley, M Choe, K Seidel, W Huang… - Nature Medicine, 2025 - nature.com
Diffuse intrinsic pontine glioma (DIPG) is a fatal central nervous system (CNS) tumor that
confers a median survival of 11 months. As B7-H3 is expressed on pediatric CNS tumors, we …
confers a median survival of 11 months. As B7-H3 is expressed on pediatric CNS tumors, we …
Fifty years of DIPG: looking at the future with hope
U Tosi, M Souweidane - Child's Nervous System, 2023 - Springer
Diffuse intrinsic pontine glioma (DIPG) is a primary brainstem tumor of childhood that carries
a dismal prognosis, with median survival of less than 1 year. Because of the brain stem …
a dismal prognosis, with median survival of less than 1 year. Because of the brain stem …
[HTML][HTML] Convection enhanced delivery for diffuse intrinsic pontine glioma: review of a single institution experience
U Tosi, M Souweidane - Pharmaceutics, 2020 - mdpi.com
Diffuse intrinsic pontine gliomas (DIPGs) are a pontine subtype of diffuse midline gliomas
(DMGs), primary central nervous system (CNS) tumors of childhood that carry a terrible …
(DMGs), primary central nervous system (CNS) tumors of childhood that carry a terrible …
Antitumor activity of the investigational B7-H3 antibody-drug conjugate, vobramitamab duocarmazine, in preclinical models of neuroblastoma
C Brignole, E Calarco, V Bensa… - Journal for …, 2023 - pmc.ncbi.nlm.nih.gov
Introduction B7-H3 is a potential target for pediatric cancers, including neuroblastoma (NB).
Vobramitamab duocarmazine (also referred to as MGC018 and herein referred to as vobra …
Vobramitamab duocarmazine (also referred to as MGC018 and herein referred to as vobra …