Recent updates of carbapenem antibiotics

MI El-Gamal, I Brahim, N Hisham, R Aladdin… - European journal of …, 2017 - Elsevier
Carbapenems are among the most commonly used and the most efficient antibiotics since
they are relatively resistant to hydrolysis by most β-lactamases, they target penicillin-binding …

A review on thermal analyses of cyclodextrins and cyclodextrin complexes

NG Hădărugă, GN Bandur, I David… - Environmental Chemistry …, 2019 - Springer
Cyclodextrins are valuable natural or synthetically modified cyclic oligosaccharides that are
widely used for ameliorating properties of biologically active compounds such as food …

Cyclodextrin: A prospective nanocarrier for the delivery of antibacterial agents against bacteria that are resistant to antibiotics

P Saha, MR Rafe - Heliyon, 2023 - cell.com
Supramolecular chemistry introduces us to the macrocyclic host cyclodextrin, which has a
hydrophobic cavity. The hydrophobic cavity has a higher affinity for hydrophobic guest …

[HTML][HTML] Cyclodextrin inclusion complexes with antibiotics and antibacterial agents as drug-delivery systems—A pharmaceutical perspective

D Boczar, K Michalska - Pharmaceutics, 2022 - mdpi.com
Cyclodextrins (CDs) are a family of cyclic oligosaccharides, consisting of a macrocyclic ring
of glucose subunits linked by α-1, 4 glycosidic bonds. The shape of CD molecules is similar …

Thermal degradation of antioxidant compounds: Effects of parameters, thermal degradation kinetics, and formulation strategies

JKU Ling, JH Sam, J Jeevanandam, YS Chan… - Food and Bioprocess …, 2022 - Springer
Stability of antioxidant compounds (AC) is always a challenging aspect in the food industry.
AC, by nature, can be easily degraded under exposure of different parameters …

Formulation of carbapenems loaded gold nanoparticles to combat multi-antibiotic bacterial resistance: In vitro antibacterial study

MA Shaker, MI Shaaban - International Journal of Pharmaceutics, 2017 - Elsevier
Despite the fact that carbapenems (powerful β-lactams antibiotics) were able to fight serious
infectious diseases, nowadays the spread of carbapenems-resistant bacteria is considered …

Oral meropenem for superbugs: challenges and opportunities

A Raza, SC Ngieng, FB Sime, PJ Cabot, JA Roberts… - Drug discovery today, 2021 - Elsevier
Highlights•Meropenem is used to treat various infections, especially from drug-resistant
bacteria.•Meropenem administration demands specialized resources and trained …

Hot melt extrusion technology for improved dissolution, solubility and “spring-parachute” processes of amorphous self-micellizing solid dispersions containing BCS II …

NQ Shi, SR Wang, Y Zhang, JS Huo, LN Wang… - European Journal of …, 2019 - Elsevier
Many strategies have been employed to improve oral drug delivery. One such approach
involves the use of supersaturable delivery systems such as amorphous self-micellizing …

[HTML][HTML] Molecular Assembly between Weak Crosslinking Cyclodextrin Polymer and trans-Cinnamaldehyde for Corrosion Inhibition towards Mild Steel in 3.5% NaCl …

Y Ma, B Fan, T Zhou, H Hao, B Yang, H Sun - Polymers, 2019 - mdpi.com
Constructing molecular assembly between a soluble cyclodextrin polymer (SCDP) and an
anticorrosive component is conducive to increasing the availability of a corrosion inhibitor …

Guest-host relationship of cyclodextrin and its pharmacological benefits

F Alshati, TAA Alahmed, F Sami, MS Ali… - Current …, 2023 - benthamdirect.com
Many methods, including solid dispersion, micellization, and inclusion complexes, have
been employed to increase the solubility of potent drugs. Beta-cyclodextrin (βCD) is a cyclic …