Among all adult somatic stem cells, those of the corneal epithelium are unique in their
exclusive location in a defined limbal structure termed Palisades of Vogt. As a result …

Aniridia, a rare congenital disease, is often characterized by a progressive, pronounced
limbal insufficiency and ocular surface pathology termed aniridia-associated keratopathy …

The anatomy of the human corneal innervation has been the subject of much investigation;
however, a comprehensive description remains elusive. The purpose of the present study …

Epithelial cell monolayers show remarkable displacement and velocity correlations over
distances of ten or more cell sizes that are reminiscent of supercooled liquids and active …

Advances in imaging and cell-labeling techniques have greatly enhanced our
understanding of developmental and neurobiological processes. Among vertebrates …

The adult mammalian cochlea lacks regenerative capacity, which is the main reason for the
permanence of hearing loss. Vestibular organs, in contrast, replace a small number of lost …

Purpose: Single-cell RNA-sequencing (scRNA-seq) was used to interrogate the relatively
rare stem (SC) and early transit amplifying (TA) cell populations in limbal/corneal epithelia …

Active systems on curved geometries are ubiquitous in the living world. In the presence of
curvature, orientationally ordered polar flocks are forced to be inhomogeneous, often …

The factors that regulate the size of organs to ensure that they fit within an organism are not
well understood. A simple organ, the ocular lens serves as a useful model with which to …

Stem cell (SC) division, deployment, and differentiation are processes that contribute to
corneal epithelial renewal. Until now studying the destiny of these cells in a living mammal …