Emerging materials for hemostasis

XF Li, P Lu, HR Jia, G Li, B Zhu, X Wang… - Coordination Chemistry …, 2023 - Elsevier
Severe hemorrhage has posed a serious threat to the health and even life of civilian and
military populations and brought serious economic losses. Consequently, it is imperative to …

Hemostasis strategies and recent advances in nanomaterials for hemostasis

J Du, J Wang, T Xu, H Yao, L Yu, D Huang - Molecules, 2023 - mdpi.com
The development of materials that effectively stop bleeding and prevent wound adhesion is
essential in both military and medical fields. However, traditional hemostasis methods, such …

Polyphosphate nanoparticles on the platelet surface trigger contact system activation

JJF Verhoef, AD Barendrecht, KF Nickel… - Blood, The Journal …, 2017 - ashpublications.org
Polyphosphate is an inorganic polymer that can potentiate several interactions in the blood
coagulation system. Blood platelets contain polyphosphate, and the secretion of platelet …

Factor XII contact activation

C Naudin, E Burillo, S Blankenberg… - … in thrombosis and …, 2017 - thieme-connect.com
Contact activation is the surface-induced conversion of factor XII (FXII) zymogen to the
serine protease FXIIa. Blood-circulating FXII binds to negatively charged surfaces and this …

Polyphosphate in thrombosis, hemostasis, and inflammation

CJ Baker, SA Smith… - Research and Practice in …, 2019 - Wiley Online Library
This illustrated review focuses on polyphosphate as a potent modulator of the plasma
clotting cascade, with possible roles in hemostasis, thrombosis, and inflammation …

Sprayable surface-adaptive biocompatible membranes for efficient hemostasis via assembly of chitosan and polyphosphate

C Liu, C Liu, Z Shi, W Lu, Z Liu, S Liu, X Wang… - Carbohydrate …, 2023 - Elsevier
This work describes a hemostatic membrane system (or surface coating) based on spray-
assisted layer-by-layer electrostatic assemblies of oppositely charged polyphosphate …

Platelets and platelet-inspired biomaterials technologies in wound healing applications

UDS Sekhon, A Sen Gupta - ACS Biomaterials Science & …, 2017 - ACS Publications
Wound healing is a complex biological process involving distinct phases of hemostasis,
immune response, and inflammatory events, regulated cellular proliferation, and matrix …

Injectable hemostat composed of a polyphosphate-conjugated hyaluronan hydrogel

M Sakoda, M Kaneko, S Ohta, P Qi, S Ichimura… - …, 2018 - ACS Publications
We have developed a new hydrogel hemostat composed of hyaluronan (HA) conjugated
with inorganic polyphosphate (PolyP). A hemostatic hydrogel, HAX-PolyP, was formed …

Vibrational spectroscopy of water with high spatial resolution

JR Jokisaari, JA Hachtel, X Hu, A Mukherjee… - Advanced …, 2018 - Wiley Online Library
The ability to examine the vibrational spectra of liquids with nanometer spatial resolution will
greatly expand the potential to study liquids and liquid interfaces. In fact, the fundamental …

Factor XII-driven inflammatory reactions with implications for anaphylaxis

L Bender, H Weidmann, S Rose-John… - Frontiers in …, 2017 - frontiersin.org
Anaphylaxis is a life-threatening allergic reaction. It is triggered by the release of pro-
inflammatory cytokines and mediators from mast cells and basophils in response to …