Rates of alcohol use disorder (AUD) have increased in women by 84% over the past ten
years relative to a 35% increase in men. This substantive increase in female drinking is …

Human neuroimaging studies suggest that neural cue reactivity is strongly associated with
indices of drug use, including addiction severity and treatment success. However, little is …

Addiction is associated with neuroplasticity in the corticostriatal brain circuitry that is
important for guiding adaptive behaviour. The hierarchy of corticostriatal information …

Altered brain responses to alcohol-associated stimuli are a neural hallmark of alcohol-use
disorder (AUD) and a promising target for pharmacotherapy. However, findings in cue …

The authors argue that human desire involves conscious cognition that has strong affective
connotation and is potentially involved in the determination of appetitive behavior rather …

Alcohol consumption is an integral part of daily life in many societies. The benefits
associated with the production, sale, and use of alcoholic beverages come at an enormous …

The present quantitative meta‐analysis set out to test whether cue‐reactivity responses in
humans differ across drugs of abuse and whether these responses constitute the biological …

Intertemporal choices are decisions with consequences that play out over time. These
choices range from the prosaic–how much food to eat at a meal–to life-changing decisions …

Rationale Animal experiments have provided evidence that the striatum and medial
prefrontal cortex play a predominant role in the acquisition and maintenance of drug …

The rat prelimbic prefrontal cortex and nucleus accumbens core are critical for initiating
cocaine seeking. In contrast, the neural circuitry responsible for inhibiting cocaine seeking …