Epithelial barrier hypothesis: effect of the external exposome on the microbiome and epithelial barriers in allergic disease
Environmental exposure plays a major role in the development of allergic diseases. The
exposome can be classified into internal (eg, aging, hormones, and metabolic processes) …
exposome can be classified into internal (eg, aging, hormones, and metabolic processes) …
Molecular mechanisms of atopic dermatitis pathogenesis
J Sroka-Tomaszewska, M Trzeciak - International journal of molecular …, 2021 - mdpi.com
Atopic dermatitis is a chronic, non-infectious inflammatory dermatosis. Acharacteristic
feature is persistent itching of the skin. The chronic, relapsing course of the disease …
feature is persistent itching of the skin. The chronic, relapsing course of the disease …
Staphylococcus epidermidis and its dual lifestyle in skin health and infection
MM Severn, AR Horswill - Nature Reviews Microbiology, 2023 - nature.com
The coagulase-negative bacterium Staphylococcus epidermidis is a member of the human
skin microbiota. S. epidermidis is not merely a passive resident on skin but actively primes …
skin microbiota. S. epidermidis is not merely a passive resident on skin but actively primes …
European guideline (EuroGuiDerm) on atopic eczema–part II: non‐systemic treatments and treatment recommendations for special AE patient populations
A Wollenberg, M Kinberger, B Arents… - Journal of the …, 2022 - Wiley Online Library
The evidence‐and consensus‐based guideline on atopic eczema was developed in
accordance with the EuroGuiDerm Guideline and Consensus Statement Development …
accordance with the EuroGuiDerm Guideline and Consensus Statement Development …
Skin microbiota–host interactions
The skin is a complex and dynamic ecosystem that is inhabited by bacteria, archaea, fungi
and viruses. These microbes—collectively referred to as the skin microbiota—are …
and viruses. These microbes—collectively referred to as the skin microbiota—are …
[HTML][HTML] Type 2 inflammation contributes to skin barrier dysfunction in atopic dermatitis
Skin barrier dysfunction, a defining feature of atopic dermatitis (AD), arises from multiple
interacting systems. In AD, skin inflammation is caused by host–environment interactions …
interacting systems. In AD, skin inflammation is caused by host–environment interactions …
[HTML][HTML] The microbiome in patients with atopic dermatitis
As an interface with the environment, the skin is a complex ecosystem colonized by many
microorganisms that coexist in an established balance. The cutaneous microbiome inhibits …
microorganisms that coexist in an established balance. The cutaneous microbiome inhibits …
Comorbidities and the impact of atopic dermatitis
JI Silverberg - Annals of Allergy, Asthma & Immunology, 2019 - Elsevier
Objective Atopic dermatitis (AD) is a chronic pruritic inflammatory skin disease with
substantial patient and population burdens. A number of comorbid health problems occur in …
substantial patient and population burdens. A number of comorbid health problems occur in …
Staphylococcus aureus and atopic dermatitis: a complex and evolving relationship
Staphylococcus aureus is frequently isolated from the skin of atopic dermatitis (AD) patients
during flares. The normal microbiota is disrupted and the diversity of the microorganisms on …
during flares. The normal microbiota is disrupted and the diversity of the microorganisms on …
Epicutaneous sensitization in the development of food allergy: what is the evidence and how can this be prevented?
There is increasing evidence regarding the importance of allergic sensitization through the
skin. In this review, we provide an overview of the atopic march and immune mechanism …
skin. In this review, we provide an overview of the atopic march and immune mechanism …