Intermediate filaments (IFs) are composed of one or more members of a large family of
cytoskeletal proteins, whose expression is cell-and tissue type-specific. Their importance in …

Intermediate filaments (IFs) constitute a major structural element of animal cells. They build
two distinct systems, one in the nucleus and one in the cytoplasm. In both cases, their major …

In this work, we investigate whether stiffening in compression is a feature of single cells and
whether the intracellular polymer networks that comprise the cytoskeleton (all of which stiffen …

Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the
structure, function, and motion of proteins for students, faculty, and researchers at all levels …

To elucidate the dynamic and functional role of a cell within the tissue it belongs to, it is
essential to understand its material properties. The cell is a viscoelastic material with highly …

Nanoindentation techniques, with high spatial resolution and force sensitivity, have recently
been moved into the center of the spotlight for measuring the mechanical properties of …

Intermediate filaments (IFs) are major constituents of the cytoskeleton and nuclear boundary
in animal cells. They are of prime importance for the functional organization of structural …

Increasing usage of next-generation sequencing techniques pushed during the last decade
cardiogenetic diagnostics leading to the identification of a huge number of genetic variants …

The diversity of epithelial functions is reflected by the expression of distinct keratin pairs that
are responsible to protect epithelial cells against mechanical stress and to act as signaling …

Intermediate filaments (IFs) are cytoskeletal polymers whose protein constituents are
encoded by a large family of differentially expressed genes. Owing in part to their properties …