Cytokines in inflammatory disease

S Kany, JT Vollrath, B Relja - International journal of molecular sciences, 2019 - mdpi.com
This review aims to briefly discuss a short list of a broad variety of inflammatory cytokines.
Numerous studies have implicated that inflammatory cytokines exert important effects with …

Oxidative stress and inflammation in osteoporosis: molecular mechanisms involved and the relationship with microRNAs

T Iantomasi, C Romagnoli, G Palmini, S Donati… - International journal of …, 2023 - mdpi.com
Osteoporosis is characterized by the alteration of bone homeostasis due to an imbalance
between osteoclastic bone resorption and osteoblastic bone formation. Estrogen deficiency …

Inflammasomes in alveolar bone loss

Y Li, J Ling, Q Jiang - Frontiers in immunology, 2021 - frontiersin.org
Bone remodeling is tightly controlled by osteoclast-mediated bone resorption and osteoblast-
mediated bone formation. Fine tuning of the osteoclast–osteoblast balance results in strict …

Melatonin and inflammation—Story of a double‐edged blade

R Hardeland - Journal of pineal research, 2018 - Wiley Online Library
Melatonin is an immune modulator that displays both pro‐and anti‐inflammatory properties.
Proinflammatory actions, which are well documented by many studies in isolated cells or …

NLRP3 inflammasome: a new target for prevention and control of osteoporosis?

N Jiang, J An, K Yang, J Liu, C Guan, C Ma… - Frontiers in …, 2021 - frontiersin.org
Osteoporosis is a systemic bone metabolism disease that often causes complications, such
as fractures, and increases the risk of death. The nucleotide-binding oligomerization domain …

Periodontal inflammation-triggered by periodontal ligament stem cell pyroptosis exacerbates periodontitis

Q Chen, X Liu, D Wang, J Zheng, L Chen… - Frontiers in cell and …, 2021 - frontiersin.org
Periodontitis is an immune inflammatory disease that leads to progressive destruction of
bone and connective tissue, accompanied by the dysfunction and even loss of periodontal …

NLRP3 inflammasome activation in inflammaging

E Latz, P Duewell - Seminars in immunology, 2018 - Elsevier
The process of aging is associated with the appearance of low-grade subclinical
inflammation, termed inflammaging, that can accelerate age-related diseases. In Western …

Pyroptosis-mediated periodontal disease

MB Sordi, RS Magini, L Panahipour… - International Journal of …, 2021 - mdpi.com
Pyroptosis is a caspase-dependent process relevant to the understanding of beneficial host
responses and medical conditions for which inflammation is central to the pathophysiology …

Homocysteine and age-associated disorders

EA Ostrakhovitch, S Tabibzadeh - Ageing research reviews, 2019 - Elsevier
There are numerous theories of aging, a process which still seems inevitable. Aging leads to
cancer and multi-systemic disorders as well as chronic diseases. Decline in age-associated …

Omentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines

SS Rao, Y Hu, PL **e, J Cao, ZX Wang, JH Liu, H Yin… - Bone research, 2018 - nature.com
Osteoporosis is a frequent complication of chronic inflammatory diseases and increases in
the pro-inflammatory cytokines make an important contribution to bone loss by promoting …