Interplay between mycobacteria and host signalling pathways
A Koul, T Herget, B Klebl, A Ullrich - Nature Reviews Microbiology, 2004 - nature.com
Pathogenesis by mycobacteria requires the exploitation of host-cell signalling pathways to
enhance the intracellular survival and persistence of the pathogen. The disruption of these …
enhance the intracellular survival and persistence of the pathogen. The disruption of these …
Mycobacterium Tuberculosis Infection and Inflammation: what is Beneficial for the Host and for the Bacterium?
SJ Sasindran, JB Torrelles - Frontiers in microbiology, 2011 - frontiersin.org
Tuberculosis is still a major health problem in the world. Initial interactions between
Mycobacterium tuberculosis and the host mark the pathway of infection and the subsequent …
Mycobacterium tuberculosis and the host mark the pathway of infection and the subsequent …
Exosomes released from macrophages infected with intracellular pathogens stimulate a proinflammatory response in vitro and in vivo
S Bhatnagar, K Shinagawa… - Blood, The Journal …, 2007 - ashpublications.org
Intracellular pathogens and the molecules they express have limited contact with the
immune system. Here, we show that macrophages infected with intracellular pathogens …
immune system. Here, we show that macrophages infected with intracellular pathogens …
[HTML][HTML] Salmonella manipulation of host signaling pathways provokes cellular transformation associated with gallbladder carcinoma
Cancer is fueled by deregulation of signaling pathways in control of cellular growth and
proliferation. These pathways are also targeted by infectious pathogens en route to …
proliferation. These pathways are also targeted by infectious pathogens en route to …
The β-glucan receptor dectin-1 functions together with TLR2 to mediate macrophage activation by mycobacteria
Pattern recognition receptors (PRRs) play an essential role in a macrophage's response to
mycobacterial infections. However, how these receptors work in concert to promote this …
mycobacterial infections. However, how these receptors work in concert to promote this …
Exosomes released from infected macrophages contain Mycobacterium avium glycopeptidolipids and are proinflammatory
Mycobacterium avium is a major opportunistic pathogen in HIV-positive individuals and is
responsible for increased morbidity and mortality in AIDS patients. M. avium express …
responsible for increased morbidity and mortality in AIDS patients. M. avium express …
IL-10 Blocks Phagosome Maturation in Mycobacterium tuberculosis–Infected Human Macrophages
Successful phagolysosomal maturation is an important innate immune response to
intracellular infection. However, Mycobacterium tuberculosis (Mtb) can manipulate and …
intracellular infection. However, Mycobacterium tuberculosis (Mtb) can manipulate and …
Exosomes Derived from M. Bovis BCG Infected Macrophages Activate Antigen-Specific CD4+ and CD8+ T Cells In Vitro and In Vivo
Activation of both CD4+ and CD8+ T cells is required for an effective immune response to an
M. tuberculosis infection. However, infected macrophages are poor antigen presenting cells …
M. tuberculosis infection. However, infected macrophages are poor antigen presenting cells …
Intracellular signalling cascades regulating innate immune responses to Mycobacteria: branching out from Toll‐like receptors
Toll‐like receptors (TLRs) recognize Mycobacterium tuberculosis (Mtb) or Mtb components
and initiate mononuclear phagocyte responses that influence both innate and adaptive …
and initiate mononuclear phagocyte responses that influence both innate and adaptive …
Exosomes isolated from mycobacteria-infected mice or cultured macrophages can recruit and activate immune cells in vitro and in vivo
More than 2 billion people are infected with Mycobacterium. tuberculosis; however, only 5–
10% of those infected will develop active disease. Recent data suggest that containment is …
10% of those infected will develop active disease. Recent data suggest that containment is …