Autism spectrum disorders (ASDs) and related neurological disorders are associated with
mutations in many genes affecting the ratio between neuronal excitation and inhibition …

Co-occurring medical disorders and associated physiological abnormalities in individuals
with autism spectrum disorder (ASD) may provide insight into causal pathways or underlying …

Idiopathic focal epilepsy (IFE) with rolandic spikes is the most common childhood epilepsy,
comprising a phenotypic spectrum from rolandic epilepsy (also benign epilepsy with …

Epileptic encephalopathies are severe brain disorders with the epileptic component
contributing to the worsening of cognitive and behavioral manifestations. Acquired epileptic …

Epilepsy-aphasia syndromes (EAS) are a group of rare, severe epileptic encephalopathies
of unknown etiology with a characteristic electroencephalogram (EEG) pattern and …

In developed countries, the majority of all violent crime is committed by a small group of
antisocial recidivistic offenders, but no genes have been shown to contribute to recidivistic …

The genetic heterogeneity of neuropsychiatric disorders is high, but some pathways
emerged, notably synaptic functioning. A large number of mutations have been described in …

Highlights•N-Methyl-d-aspartate receptors (NMDARs) diversity in brain is briefly
described.•We review recent studies on NMDAR subunit mutations in neurodevelopmental …

There is an increasing recognition of clinical overlap in patients presenting with epilepsy
and autism spectrum disorder (ASD), and a great deal of new information regarding the …

Autism spectrum disorders and epilepsy commonly co-occur. In this review, we consider
some unresolved questions regarding the temporal relationship, causal mechanisms, and …