Purpose This review provides an update on the current clinical, epidemiological and
pathophysiological evidence alongside the diagnostic, prevention and treatment approach …

Abstract Paclitaxel (Brand name Taxol) is widely used in the treatment of common cancers
like breast, ovarian and lung cancer. Although highly effective in blocking tumor progression …

Multiple pathological mechanisms are involved in the development of chemotherapy-
induced peripheral neurotoxicity (CIPN). Recent work has provided insights into the …

Pharmacological strategies for chemotherapy-induced peripheral neurotoxicity (CIPN) are
very limited. We systematically reviewed data on rehabilitation, exercise, physical therapy …

One of the most relevant dose-limiting adverse effects of platinum drugs is the development
of a sensory peripheral neuropathy that highly impairs the patients' quality of life. Nowadays …

The clinical spectrum of small fiber neuropathy (SFN) encompasses manifestations related
to the involvement of thinly myelinated A‐delta and unmyelinated C fibers, including not only …

Bortezomib is the first-line standard and most effective chemotherapeutic for multiple
myeloma; however, bortezomib-induced peripheral neuropathy (BIPN) severely affects the …

Importance Chemotherapy-induced peripheral neuropathy (CIPN) is a substantial adverse
effect of anticancer treatments. As such, the assessment of CIPN remains critically important …

Simple Summary Cancer survivors can experience neurological complications after
exposure to anticancer therapy. Chemotherapy-induced peripheral neurotoxicity (CIPN) …

Our ability to quickly detect and respond to harmful environmental stimuli is vital for our
safety and survival. This inherent acute pain detection is a “gift” because it both protects our …