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The mucus clearance system is the dominant mechanical host defense system of the human
lung. Mucus is cleared from the lung by cilia and airflow, including both two-phase gas-liquid …

Background Bronchiectasis is a heterogeneous, neglected disease with few multicentre
studies exploring the causes, severity, microbiology, and treatment of the disease across …

Formerly regarded as a rare disease, bronchiectasis is increasingly recognised. A renewed
interest in this disease has led to significant progress in bronchiectasis research …

Background and objective Asthma and chronic obstructive pulmonary disease (COPD) are
two prevalent and complex diseases that require personalized management. Although a …

Background International guidelines recommend airway clearance management as one of
the important pillars of bronchiectasis treatment. However, the extent to which airway …

Background Bronchiectasis can result from infectious, genetic, immunological and allergic
causes. 60–80% of cases are idiopathic, but a well-recognised genetic cause is the motile …

Bronchiectasis is marked by bronchial dilatation, recurrent infections and significant
morbidity, underpinned by a complex interplay between microbial dysbiosis and immune …

Introduction: Pseudomonas aeruginosa is the most commonly isolated pathogen in
bronchiectasis and is associated with worse outcomes. Eradication treatment is …

Background CT is the standard method used to assess bronchiectasis. A higher airway-to-
artery diameter ratio (AAR) is typically used to identify enlarged bronchi and bronchiectasis; …