Sleep and wakefulness disturbances in Parkinson's disease: A meta-analysis on prevalence and clinical aspects of REM sleep behavior disorder, excessive daytime …

G Maggi, C Vitale, F Cerciello, G Santangelo - Sleep medicine reviews, 2023 - Elsevier
Sleep disorders (SDs) are common non-motor symptoms of Parkinson's disease (PD) with
wide variability in their prevalence rates. The etiology of SDs in PD is multifactorial because …

α-Synuclein pathology as a target in neurodegenerative diseases

H Park, TI Kam, VL Dawson, TM Dawson - Nature Reviews Neurology, 2024 - nature.com
Abstract α-Synuclein misfolds into pathological forms that lead to various neurodegenerative
diseases known collectively as α-synucleinopathies. In this Review, we provide a …

Pharmacological and non-pharmacological treatments of sleep disorders in Parkinson's disease

R Taximaimaiti, X Luo, XP Wang - Current Neuropharmacology, 2021 - benthamdirect.com
Sleep disorders are one of the most common non-motor symptoms in Parkinson's disease
(PD). It can cause a notable decrease in quality of life and functioning in PD patients, as well …

Sex differences in rapid eye movement sleep behavior disorder: a systematic review and meta-analysis

X Li, Q Zong, L Liu, Y Liu, Y Shen, X Tang… - Sleep Medicine …, 2023 - Elsevier
Although rapid eye movement (REM) sleep behavior disorder (RBD) has been widely
considered as a male-predominant parasomnia, the existing evidence for the sex difference …

Isolated REM sleep behaviour disorder: current diagnostic procedures and emerging new technologies

S Bramich, A King, M Kuruvilla, SL Naismith… - Journal of …, 2022 - Springer
Isolated REM sleep behaviour disorder (iRBD) is characterised by dream enactment
behaviours, such as kicking and punching while asleep, and vivid/violent dreams. It is now …

Common sleep disorders in adults: diagnosis and management

S Holder, NS Narula - American family physician, 2022 - aafp.org
Sleep disorders are common in the general adult population and are associated with
adverse effects such as motor vehicle collisions, decreased quality of life, and increased …

Current update on clinically relevant sleep issues in Parkinson's disease: a narrative review

K Suzuki - Journal of Parkinson's Disease, 2021 - journals.sagepub.com
Sleep disturbances are among the common nonmotor symptoms in patients with Parkinson's
disease (PD). Sleep can be disrupted by nocturnal motor and nonmotor symptoms and other …

Electroencephalogram rhythmic and arrhythmic spectral components and functional connectivity at resting state may predict the development of synucleinopathies in …

J Hernandez, JM Lina, J Dubé, A Lafrenière… - Sleep, 2024 - academic.oup.com
Abstract Study Objectives Idiopathic/isolated rapid eye movement-sleep behavior disorder
(iRBD) often precedes the onset of synucleinopathies. Here, we investigated whether …

[HTML][HTML] Alpha Synuclein Toxicity and Non-Motor Parkinson's

GM Mazzotta, C Conte - Cells, 2024 - mdpi.com
Parkinson's disease (PD) is a common multisystem neurodegenerative disorder affecting
1% of the population over the age of 60 years. The main neuropathological features of PD …

Body-first subtype of Parkinson's disease with probable REM-sleep behavior disorder is associated with non-motor dominant phenotype

L Pavelka, A Rauschenberger… - Journal of …, 2022 - content.iospress.com
Background: The hypothesis of body-first vs. brain-first subtype of PD has been proposed
with REM-Sleep behavior disorder (RBD) defining the former. The body-first PD presumes …