[HTML][HTML] Recent advances in age-related macular degeneration therapies

M Fabre, L Mateo, D Lamaa, S Baillif, G Pagès… - Molecules, 2022 - mdpi.com
Age-related macular degeneration (AMD) was described for the first time in the 1840s and is
currently the leading cause of blindness for patients over 65 years in Western Countries …

The future application of artificial intelligence and telemedicine in the retina: A perspective

CT Wu, TY Lin, CJ Lin, DK Hwang - Taiwan Journal of …, 2023 - journals.lww.com
The development of artificial intelligence (AI) and deep learning provided precise image
recognition and classification in the medical field. Ophthalmology is an exceptional …

Melatonin inhibits VEGF-induced endothelial progenitor cell angiogenesis in neovascular age-related macular degeneration

LW Lin, SW Wang, WC Huang, TK Huynh, CY Lai… - Cells, 2023 - mdpi.com
Neovascular age-related macular degeneration (AMD) is described as abnormal
angiogenesis in the retina and the leaking of fluid and blood that generates a huge, dark …

Scale-adaptive model for detection and grading of age-related macular degeneration from color retinal fundus images

NN El-Den, A Naglah, M Elsharkawy, M Ghazal… - Scientific Reports, 2023 - nature.com
Abstract Age-related Macular Degeneration (AMD), a retinal disease that affects the macula,
can be caused by aging abnormalities in number of different cells and tissues in the retina …

Mesenchymal stromal cell secretome is affected by tissue source and donor age

AJ Turlo, DE Hammond, KA Ramsbottom, J Soul… - Stem Cells, 2023 - academic.oup.com
Variation in mesenchymal stromal cell (MSC) function depending on their origin is
problematic, as it may confound clinical outcomes of MSC therapy. Current evidence …

Vision and hearing problems and psychosocial outcomes: longitudinal evidence from the German Ageing Survey

A Hajek, RM Gyasi, B Kretzler, HH König - Social psychiatry and …, 2024 - Springer
Purpose To examine whether changes in vision and hearing problems are associated with
changes in psychosocial outcomes (in terms of depressive symptoms, loneliness, and …

Intravitreal vascular endothelial growth factor inhibitor therapy in Denmark and 5-year projections

BS Thinggaard, F Pedersen, J Grauslund… - JAMA Network …, 2023 - jamanetwork.com
The introduction of intravitreal vascular endothelial growth factor (VEGF) inhibitor therapy
has revolutionized treatment for neovascular age-related macular degeneration (nAMD) …

Ultrahigh‐efficacy VEGF neutralization using carbonized nanodonuts: implications for intraocular anti‐angiogenic therapy

HJ Jian, A Anand, JY Lai, CC Huang… - Advanced …, 2024 - Wiley Online Library
Ocular angiogenesis, associated with diseases such as retinopathy of prematurity and
diabetic retinopathy, is a leading cause of irreversible vision loss. Herein, carbon …

Epidemiology, health policy and public health implications of visual impairment and age-related eye diseases in mainland China

C Li, B Zhu, J Zhang, P Guan, G Zhang, H Yu… - Frontiers in Public …, 2022 - frontiersin.org
The prevalence of visual impairment (VI) and age-related eye diseases has increased
dramatically with the growing aging population in mainland China. However, there is limited …

Mechanistic insight into age-related macular degeneration (AMD): anatomy, epidemiology, genetics, pathogenesis, prevention, implications, and treatment strategies …

MA Amini, A Karbasi, M Vahabirad… - Chonnam Medical …, 2023 - pmc.ncbi.nlm.nih.gov
One of the most complicated eye disorders is age-related macular degeneration (AMD)
which is the leading cause of irremediable blindness all over the world in the elderly. AMD is …