[HTML][HTML] Which structure generates paradoxical (REM) sleep: The brainstem, the hypothalamus, the amygdala or the cortex?

PH Luppi, A Chancel, J Malcey, S Cabrera, P Fort… - Sleep Medicine …, 2024 - Elsevier
Paradoxical or Rapid eye movement (REM) sleep (PS) is a state characterized by REMs,
EEG activation and muscle atonia. In this review, we discuss the contribution of brainstem …

Neural and homeostatic regulation of REM sleep

SH Park, F Weber - Frontiers in psychology, 2020 - frontiersin.org
Rapid eye movement (REM) sleep is a distinct, homeostatically controlled brain state
characterized by an activated electroencephalogram (EEG) in combination with paralysis of …

Evolutionary origin of distinct NREM and REM sleep

R Yamazaki, H Toda, PA Libourel, Y Hayashi… - Frontiers in …, 2020 - frontiersin.org
Sleep is mandatory in most animals that have the nervous system and is universally
observed in model organisms ranging from the nematodes, zebrafish, to mammals …

Is REM sleep a paradoxical state?: Different neurons are activated in the cingulate cortices and the claustrum during wakefulness and paradoxical sleep hypersomnia

R Maciel, R Yamazaki, D Wang, A De Laet… - Biochemical …, 2021 - Elsevier
Michel Jouvet proposed in 1959 that REM sleep is a paradoxical state since it was
characterized by the association of a cortical activation similar to wakefulness (W) with …

Lateral hypothalamic neuronal ensembles regulate pre-sleep nest-building behavior

MI Sotelo, J Tyan, C Markunas, BA Sulaman, L Horwitz… - Current Biology, 2022 - cell.com
The transition from wakefulness to sleep requires striking alterations in brain activity,
physiology, and behavior, yet the precise neuronal circuit elements facilitating this transition …

Granule cells in the infrapyramidal blade of the dentate gyrus are activated during paradoxical (REM) sleep hypersomnia but not during wakefulness: a study using …

R Yamazaki, D Wang, A De Laet, R Maciel, C Agnorelli… - Sleep, 2021 - academic.oup.com
Abstract Study Objectives Determine whether in the hippocampus and the supramammillary
nucleus (SuM) the same neurons are reactivated when mice are exposed 1 week apart to …

Neuronal network controlling REM sleep

PH Luppi, J Malcey, A Chancel, B Duval… - Journal of Sleep …, 2024 - Wiley Online Library
Rapid eye movement sleep is a state characterized by concomitant occurrence of rapid eye
movements, electroencephalographic activation and muscle atonia. In this review, we …

Anatomical substrates of rapid eye movement sleep rebound in a rodent model of post-sevoflurane sleep disruption

N Atluri, E Dulko, M Jedrusiak, J Klos, HP Osuru… - …, 2024 - ingentaconnect.com
Background: Previous research suggests that sevoflurane anesthesia may prevent the brain
from accessing rapid eye movement (REM) sleep. If true, then patterns of neural activity …

Dopamine neurons in the ventral tegmental area modulate rapid eye movement sleep

JJ Fraigne, PH Luppi, CE Mahoney, R De Luca… - Sleep, 2023 - academic.oup.com
The discovery of REM sleep is attributed to the landmark observations of Eugene Aserinsky
and Nathaniel Kleitman. In 1953, they identified periods of „active sleep‟ that are marked by …

Projections from LIM homeobox 6 (Lhx6)+ zona incerta neurons to the cholinergic or monoaminergic nuclei of the rat

SG Oh, EY Lee, HS Lee - The Anatomical Record, 2023 - Wiley Online Library
A recent report suggested that LIM homeobox 6 (Lhx6)+ GABA‐releasing neurons of the
ventral zona incerta (VZI) promote sleep, particularly paradoxical sleep (PS). While their …