Mechanisms in endocrinology: vitamin D and COVID-19

JP Bilezikian, D Bikle, M Hewison… - European journal of …, 2020 - academic.oup.com
The SARS-CoV-2 virus responsible for the COVID-19 pandemic has generated an explosion
of interest both in the mechanisms of infection leading to dissemination and expression of …

An update on the effects of vitamin D on the immune system and autoimmune diseases

C Sîrbe, S Rednic, A Grama, TL Pop - International journal of molecular …, 2022 - mdpi.com
Vitamin D intervenes in calcium and phosphate metabolism and bone homeostasis.
Experimental studies have shown that 1, 25-dihydroxyvitamin D (calcitriol) generates …

[HTML][HTML] Vitamin D's effect on immune function

PJ Martens, C Gysemans, A Verstuyf, C Mathieu - Nutrients, 2020 - mdpi.com
Ever since its discovery by Windhaus, the importance of the active metabolite of vitamin D (1,
25-dihydroxyvitamin D 3; 1, 25-(OH) 2D 3) has been ever expanding. In this review, the …

Immune system dysregulation during spaceflight: potential countermeasures for deep space exploration missions

BE Crucian, A Choukèr, RJ Simpson, S Mehta… - Frontiers in …, 2018 - frontiersin.org
Recent studies have established that dysregulation of the human immune system and the
reactivation of latent herpesviruses persists for the duration of a 6-month orbital spaceflight …

Vitamin D, autoimmune disease and rheumatoid arthritis

SR Harrison, D Li, LE Jeffery, K Raza… - Calcified tissue …, 2020 - Springer
Vitamin D has been reported to influence physiological systems that extend far beyond its
established functions in calcium and bone homeostasis. Prominent amongst these are the …

Modulation of the immune response to respiratory viruses by vitamin D

CL Greiller, AR Martineau - Nutrients, 2015 - mdpi.com
Background: Vitamin D deficiency has been shown to be independently associated with
increased risk of viral acute respiratory infection (ARI) in a number of observational studies …

The impact of vitamin D on skin aging

G Bocheva, RM Slominski, AT Slominski - International Journal of …, 2021 - mdpi.com
The active metabolites of vitamin D3 (D3) and lumisterol (L3) exert a variety of antiaging and
photoprotective effects on the skin. These are achieved through immunomodulation and …

Vitamin D: effect on haematopoiesis and immune system and clinical applications

M Medrano, E Carrillo-Cruz, I Montero… - International journal of …, 2018 - mdpi.com
Vitamin D is a steroid-like hormone which acts by binding to vitamin D receptor (VDR). It
plays a main role in the calcium homeostasis and metabolism. In addition, vitamin D display …

Vitamin D inhibits monocyte/macrophage proinflammatory cytokine production by targeting MAPK phosphatase-1

Y Zhang, DYM Leung, BN Richers, Y Liu… - The Journal of …, 2012 - journals.aai.org
It is estimated that 1 billion people around the world are vitamin D deficient. Vitamin D
deficiency has been linked to various inflammatory diseases. However, the mechanism by …

Regulation of immune function by vitamin D and its use in diseases of immunity

AS Vanherwegen, C Gysemans… - … and Metabolism Clinics, 2017 - endo.theclinics.com
The immune system, innate and adaptive, is a highly evolved and complex network,
essential for promoting survival in an environment full of potential pathogens, while …