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Detection and analysis of chiral molecules as disease biomarkers
The chirality of small metabolic molecules is important in controlling physiological processes
and indicating the health status of humans. Abnormal enantiomeric ratios of chiral molecules …
and indicating the health status of humans. Abnormal enantiomeric ratios of chiral molecules …
Interactions of glial cells with neuronal synapses, from astrocytes to microglia and oligodendrocyte lineage cells
The mammalian brain is a complex organ comprising neurons, glia, and more than 1× 1014
synapses. Neurons are a heterogeneous group of electrically active cells, which form the …
synapses. Neurons are a heterogeneous group of electrically active cells, which form the …
A1/A2 astrocytes in central nervous system injuries and diseases: Angels or devils?
YY Fan, J Huo - Neurochemistry International, 2021 - Elsevier
Astrocytes play a pivotal role in maintaining the central nervous system (CNS) homeostasis
and function. In response to CNS injuries and diseases, reactive astrocytes are triggered. By …
and function. In response to CNS injuries and diseases, reactive astrocytes are triggered. By …
Barcoded viral tracing of single-cell interactions in central nervous system inflammation
INTRODUCTION Glial cells of the central nervous system (CNS), including astrocytes and
microglia, play critical roles in development, tissue repair, and homeostasis. However …
microglia, play critical roles in development, tissue repair, and homeostasis. However …
Glutamate hypothesis in schizophrenia
Y Uno, JT Coyle - Psychiatry and clinical neurosciences, 2019 - Wiley Online Library
Schizophrenia is a chronic and severe psychiatric disorder that has profound impact on an
individual's life and on society. Thus, develo** more effective therapeutic interventions is …
individual's life and on society. Thus, develo** more effective therapeutic interventions is …
The synapse in traumatic brain injury
Traumatic brain injury (TBI) is a leading cause of death and disability worldwide and is a risk
factor for dementia later in life. Research into the pathophysiology of TBI has focused on the …
factor for dementia later in life. Research into the pathophysiology of TBI has focused on the …
Dual roles of astrocytes in plasticity and reconstruction after traumatic brain injury
Traumatic brain injury (TBI) is one of the leading causes of fatality and disability worldwide.
Despite its high prevalence, effective treatment strategies for TBI are limited. Traumatic brain …
Despite its high prevalence, effective treatment strategies for TBI are limited. Traumatic brain …
[HTML][HTML] Pathophysiological responses and roles of astrocytes in traumatic brain injury
S Michinaga, Y Koyama - International journal of molecular sciences, 2021 - mdpi.com
Traumatic brain injury (TBI) is immediate damage caused by a blow to the head resulting
from traffic accidents, falls, and sporting activity, which causes death or serious disabilities in …
from traffic accidents, falls, and sporting activity, which causes death or serious disabilities in …
The role of astrocytic α7 nicotinic acetylcholine receptors in Alzheimer disease
IC Fontana, A Kumar, A Nordberg - Nature Reviews Neurology, 2023 - nature.com
The ongoing search for therapeutic interventions in Alzheimer disease (AD) has highlighted
the complexity of this condition and the need for additional biomarkers, beyond amyloid-β …
the complexity of this condition and the need for additional biomarkers, beyond amyloid-β …
Ion channels and electrophysiological properties of astrocytes: implications for emergent stimulation technologies
Astrocytes comprise a heterogeneous cell population characterized by distinct
morphologies, protein expression and function. Unlike neurons, astrocytes do not generate …
morphologies, protein expression and function. Unlike neurons, astrocytes do not generate …