Spinal cord injury (SCI) constitutes an inestimable public health issue. The most crucial
phase in the pathophysiological process of SCI concerns the well-known secondary injury …

Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …

Transected axons fail to regrow in the mature central nervous system. Astrocytic scars are
widely regarded as causal in this failure. Here, using three genetically targeted loss-of …

Surgical repair of severe peripheral nerve injuries represents not only a pressing medical
need, but also a great clinical challenge. Autologous nerve grafting remains a golden …

Spinal cord injury (SCI) can lead to paraplegia or quadriplegia. Although there are no fully
restorative treatments for SCI, various rehabilitative, cellular and molecular therapies have …

The low regeneration potential of the central nervous system (CNS) represents a challenge
for the development of new therapeutic strategies. Mesenchymal stem cells (MSCs) have …

Cell transplantation therapies have become a major focus in pre-clinical research as a
promising strategy for the treatment of spinal cord injury (SCI). In this article, we …

The regenerative capacity of injured adult mammalian central nervous system (CNS) tissue
is very limited. Disease or injury that causes destruction or damage to neuronal networks …

Spinal cord injury (SCI) is a devastating condition producing great personal and societal
costs and for which there is no effective treatment. Stem cell transplantation is a promising …

Transplantation of bone marrow-derived mesenchymal stromal cells (MSCs) into the injured
brain or spinal cord may provide therapeutic benefit. Several models of central nervous …