Although the treatment of myocardial infarction (MI) has improved considerably, it is still a
worldwide disease with high morbidity and high mortality. Whilst there is still a long way to …

Damage-associated molecular patterns (DAMPs) are endogenous danger molecules that
are released from damaged or dying cells and activate the innate immune system by …

S100A8 and S100A9 (also known as MRP8 and MRP14, respectively) are Ca2+ binding
proteins belonging to the S100 family. They often exist in the form of heterodimer, while …

Characterizing the transcriptome of individual cells is fundamental to understanding
complex biological systems. We describe a droplet-based system that enables 3′ mRNA …

The emerging single-cell RNA sequencing (scRNA-seq) technologies enable the
investigation of transcriptomic landscapes at the single-cell resolution. ScRNA-seq data …

The S100 proteins, a family of calcium-binding cytosolic proteins, have a broad range of
intracellular and extracellular functions through regulating calcium balance, cell apoptosis …

An effective resolution program may be able to prevent the progression from non-resolving
acute inflammation to persistent chronic inflammation. It has now become evident that …

Chronic obstructive pulmonary disease (COPD) is the third leading cause of morbidity and
death worldwide. Inhalation of cigarette smoke (CS) is the major cause in developed …

The peripheral nervous system (PNS) has remarkable regenerative abilities after injury.
Successful PNS regeneration relies on both injured axons and non-neuronal cells, including …

Toll-like receptors (TLRs) are a family of pattern recognition receptors involved in
cardiovascular diseases. Notably, numerous studies have demonstrated that TLR4 activates …