[HTML][HTML] Therapeutic nanoparticles and their targeted delivery applications

AA Yetisgin, S Cetinel, M Zuvin, A Kosar, O Kutlu - Molecules, 2020 - mdpi.com
Nanotechnology offers many advantages in various fields of science. In this regard,
nanoparticles are the essential building blocks of nanotechnology. Recent advances in …

A framework for designing delivery systems

W Poon, BR Kingston, B Ouyang, W Ngo… - Nature …, 2020 - nature.com
The delivery of medical agents to a specific diseased tissue or cell is critical for diagnosing
and treating patients. Nanomaterials are promising vehicles to transport agents that include …

Why nanoparticles prefer liver macrophage cell uptake in vivo

W Ngo, S Ahmed, C Blackadar, B Bussin, Q Ji… - Advanced Drug Delivery …, 2022 - Elsevier
Effective delivery of therapeutic and diagnostic nanoparticles is dependent on their ability to
accumulate in diseased tissues. However, most nanoparticles end up in liver macrophages …

Recent developments in the facile bio-synthesis of gold nanoparticles (AuNPs) and their biomedical applications

KX Lee, K Shameli, YP Yew, SY Teow… - International journal …, 2020 - Taylor & Francis
Gold nanoparticles (AuNPs) are extensively studied nanoparticles (NPs) and are known to
have profound applications in medicine. There are various methods to synthesize AuNPs …

Gold nanoparticle based photothermal therapy: Development and application for effective cancer treatment

W Yang, H Liang, S Ma, D Wang, J Huang - Sustainable Materials and …, 2019 - Elsevier
Recent advances in nanomedicine make it auspicious for cancer diagnosis and treatment. A
possible non-invasive photothermal therapy (PTT) for cancer treatment could be constructed …

Emerging nanotechnology and advanced materials for cancer radiation therapy

G Song, L Cheng, Y Chao, K Yang, Z Liu - Advanced materials, 2017 - Wiley Online Library
Radiation therapy (RT) including external beam radiotherapy (EBRT) and internal
radioisotope therapy (RIT) has been widely used for clinical cancer treatment. However …

Metallic nanoparticles as drug delivery system for the treatment of cancer

N Desai, M Momin, T Khan, S Gharat… - Expert opinion on …, 2021 - Taylor & Francis
Introduction The targeted delivery of anticancer agents to tumor is a major challenge
because most of the drugs show off-target effect resulting in nonspecific cell death …

Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination

YN Zhang, W Poon, AJ Tavares, ID McGilvray… - Journal of controlled …, 2016 - Elsevier
99% of administered nanoparticles will accumulate and sequester in the liver after
administration into the body. This results in reduced delivery to the targeted diseased tissue …

Nanoparticle uptake: the phagocyte problem

HH Gustafson, D Holt-Casper, DW Grainger… - Nano today, 2015 - Elsevier
Phagocytes are key cellular participants determining important aspects of host exposure to
nanomaterials, initiating clearance, biodistribution and the tenuous balance between host …

Principles of nanoparticle delivery to solid tumors

WCW Chan - BME frontiers, 2023 - spj.science.org
The effective treatment of patients with cancer hinges on the delivery of therapeutics to a
tumor site. Nanoparticles provide an essential transport system. We present 5 principles to …