Viruses are widely used as vectors for heterologous gene expression in cultured cells or
natural hosts, and therefore a large number of viruses with exogenous sequences inserted …

The homeodomain transcription factor Crx is required for expression of many photoreceptor
genes in the mammalian retina. The mechanism by which Crx activates transcription …

The outbreaks of viral hemorrhagic septicemia (VHS) and viral encephalopathy and
retinopathy (VER) caused by the enveloped novirhabdovirus VHSV, and the non-enveloped …

Determining the fitness of viral genotypes has become a standard practice in virology as it is
essential to evaluate their evolutionary potential. Darwinian fitness, defined as the …

We describe a new method to accomplish multiplexed, absolute protein quantification in a
targeted fashion. The approach draws upon the recently developed neutron encoding …

Sequence overlap between two genes is common across all genomes, with viruses having
high proportions of these gene overlaps. Genome modularization and refactoring is the …

The order in which genes are organized within a genome is generally not conserved
between distantly related species. However, within virus orders and families, strong …

Cellular biology has a uniformity not shared amongst viruses. This is perhaps best
exemplified by negative-sense RNA viruses that encode their genetic material as a …

Determining the fitness of viral genotypes has become a standard practice in virology as it is
essential to evaluate their evolutionary potential. Darwinian fitness, defined as the …

Experimental evolution studies offer the possibility to examine whether closely related
populations converge versus diverge in phenotype and genotype, when challenged to adapt …