New and emerging targeted therapies for advanced breast cancer
KH Lau, AM Tan, Y Shi - International journal of molecular sciences, 2022 - mdpi.com
In the United States, breast cancer is among the most frequently diagnosed cancers in
women. Breast cancer is classified into four major subtypes: human epidermal growth factor …
women. Breast cancer is classified into four major subtypes: human epidermal growth factor …
Sodium alginate based drug delivery in management of breast cancer
Among women, breast cancer (B· C.) is a common form of cancer that can strike either
developed or develo** countries. In addition to pregnancy-related variables, hormone …
developed or develo** countries. In addition to pregnancy-related variables, hormone …
Molecular perspective on targeted therapy in breast cancer: a review of current status
B Demir Cetinkaya, C Biray Avci - Medical Oncology, 2022 - Springer
Breast cancer is categorized at the molecular level according to the status of certain
hormone and growth factor receptors, and this classification forms the basis of current …
hormone and growth factor receptors, and this classification forms the basis of current …
Molecular pathways and therapeutic targets linked to triple-negative breast cancer (TNBC)
Cancer is a group of diseases characterized by uncontrolled cellular growth, abnormal
morphology, and altered proliferation. Cancerous cells lose their ability to act as anchors …
morphology, and altered proliferation. Cancerous cells lose their ability to act as anchors …
Cancer therapy and treatments during COVID-19 era
SM Akula, SL Abrams, LS Steelman, S Candido… - Advances in biological …, 2020 - Elsevier
The COVID-19 pandemic has put a serious strain on health treatments as well at the
economies of many nations. Unfortunately, there is not currently available vaccine for SARS …
economies of many nations. Unfortunately, there is not currently available vaccine for SARS …
Neoadjuvant Talazoparib in Patients With Germline BRCA1/2 Mutation-Positive, Early-Stage Triple-Negative Breast Cancer: Results of a Phase II Study
JK Litton, JT Beck, JM Jones, J Andersen… - The …, 2023 - academic.oup.com
Background The undetermined efficacy of the current standard-of-care neoadjuvant
treatment, anthracycline/platinum-based chemotherapy, in patients with early-stage triple …
treatment, anthracycline/platinum-based chemotherapy, in patients with early-stage triple …
Functional RECAP (REpair CAPacity) assay identifies homologous recombination deficiency undetected by DNA-based BRCAness tests
TG Meijer, L Nguyen, A Van Hoeck, AM Sieuwerts… - Oncogene, 2022 - nature.com
Germline BRCA1/2 mutation status is predictive for response to Poly-[ADP-Ribose]-
Polymerase (PARP) inhibitors in breast cancer (BC) patients. However, non-germline …
Polymerase (PARP) inhibitors in breast cancer (BC) patients. However, non-germline …
[HTML][HTML] Trailblazing perspectives on targeting breast cancer stem cells
Breast cancer (BCa) is one of the most prevalent malignant tumors affecting women's health
worldwide. The recurrence and metastasis of BCa have made it a long-standing challenge …
worldwide. The recurrence and metastasis of BCa have made it a long-standing challenge …
Risk of pneumonitis in cancer patients treated with PARP inhibitors: a meta-analysis of randomized controlled trials and a pharmacovigilance study of the FAERS …
Z Ma, X Sun, Z Zhao, W Lu, Q Guo, S Wang, J You… - Gynecologic …, 2021 - Elsevier
Abstract Objective/Background We aimed to evaluate the risk of PARP inhibitors (PARPis)
causing pneumonitis in randomized controlled trials (RCTs) and in the real-world practice …
causing pneumonitis in randomized controlled trials (RCTs) and in the real-world practice …
[HTML][HTML] Diabetes-associated breast cancer is molecularly distinct and shows a DNA damage repair deficiency
Diabetes commonly affects patients with cancer. We investigated the influence of diabetes
on breast cancer biology using a 3-pronged approach that included analysis of orthotopic …
on breast cancer biology using a 3-pronged approach that included analysis of orthotopic …