The human immunodeficiency virus (HIV) persists in latently infected CD4+ T cells and
integrates with the host genome until cell death. Acquired immunodeficiency syndrome …

In the pursuit of achieving better therapeutic outcomes in the treatment of HIV, innovative
drug delivery strategies have been extensively explored. Mannose receptors, which are …

One of the critical steps in gene therapy is the successful delivery of the genes.
Immunogenicity and toxicity are major issues for viral gene delivery systems. Thus, non-viral …

Since the beginning of the coronavirus pandemic in late 2019, viral infections have become
one of the top three causes of mortality worldwide. Immunization and the use of …

Highly active anti-retroviral therapy (HAART) is prescribed for HIV infection and, to a certain
extent, limits the infection's spread. However, it cannot completely eradicate the latent virus …

Abstract The Blood-Brain Barrier (BBB) significantly impedes drug delivery to the central
nervous system. Nanotechnology, especially surface-functionalized lipid nanoparticles …

The human immunodeficiency virus (HIV) is the primary cause of acquired immune
deficiency syndrome (AIDS), one of the deadliest pandemic diseases. Various mechanisms …

There is a dire need for dual-long-acting therapy that could simultaneously target different
stages of the HIV life cycle and providing a dual-prolonged strategy for improved anti-HIV …

Abstract Background Nanosuspension-loaded microneedles (MNs) are an emerging and
advanced strategy used extensively to formulate lipophilic molecules by embedding them …

The present investigation aims to develop and explore mannosylated lipid-based carriers to
deliver an anti-HIV drug, Etravirine (TMC) and Selenium nanoparticles (SeNPs), to the HIV …