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Integration of molecular docking analysis and molecular dynamics simulations for studying food proteins and bioactive peptides
In silico tools, such as molecular docking, are widely applied to study interactions and
binding affinity of biological activity of proteins and peptides. However, restricted sampling of …
binding affinity of biological activity of proteins and peptides. However, restricted sampling of …
Review and perspective on bioactive peptides: A roadmap for research, development, and future opportunities
Bioactive peptides (BPs) possess a broad spectrum of beneficial effects, such as antioxidant,
antihypertensive, antidiabetic, anticancer, anti-inflammatory, antimicrobial, and anti-aging …
antihypertensive, antidiabetic, anticancer, anti-inflammatory, antimicrobial, and anti-aging …
UniDL4BioPep: a universal deep learning architecture for binary classification in peptide bioactivity
Identification of potent peptides through model prediction can reduce benchwork in wet
experiments. However, the conventional process of model buildings can be complex and …
experiments. However, the conventional process of model buildings can be complex and …
BERT4Bitter: a bidirectional encoder representations from transformers (BERT)-based model for improving the prediction of bitter peptides
Motivation The identification of bitter peptides through experimental approaches is an
expensive and time-consuming endeavor. Due to the huge number of newly available …
expensive and time-consuming endeavor. Due to the huge number of newly available …
StackIL6: a stacking ensemble model for improving the prediction of IL-6 inducing peptides
P Charoenkwan, W Chiangjong… - Briefings in …, 2021 - academic.oup.com
The release of interleukin (IL)-6 is stimulated by antigenic peptides from pathogens as well
as by immune cells for activating aggressive inflammation. IL-6 inducing peptides are …
as by immune cells for activating aggressive inflammation. IL-6 inducing peptides are …
Strengths and limitations of in silico tools to assess physicochemical properties, bioactivity, and bioavailability of food-derived peptides
F Rivero-Pino, MC Millan-Linares… - Trends in Food Science …, 2023 - Elsevier
Background Bioactive peptides obtained from different food sources have been proved to
exert several bioactivities, such as antioxidant, antihypertensive, antimicrobial, or anti …
exert several bioactivities, such as antioxidant, antihypertensive, antimicrobial, or anti …
Advances in machine learning screening of food bioactive compounds
Y Zhang, X Bao, Y Zhu, Z Dai, Q Shen, Y Xue - Trends in Food Science & …, 2024 - Elsevier
Background Food contains abundant bioactive compounds that play a crucial role in human
health. However, conventional methods for screening food bioactive compounds (FBCs) are …
health. However, conventional methods for screening food bioactive compounds (FBCs) are …
DeepIPs: comprehensive assessment and computational identification of phosphorylation sites of SARS-CoV-2 infection using a deep learning-based approach
The rapid spread of SARS-CoV-2 infection around the globe has caused a massive health
and socioeconomic crisis. Identification of phosphorylation sites is an important step for …
and socioeconomic crisis. Identification of phosphorylation sites is an important step for …
AMYPred-FRL is a novel approach for accurate prediction of amyloid proteins by using feature representation learning
Amyloid proteins have the ability to form insoluble fibril aggregates that have important
pathogenic effects in many tissues. Such amyloidoses are prominently associated with …
pathogenic effects in many tissues. Such amyloidoses are prominently associated with …
ATSE: a peptide toxicity predictor by exploiting structural and evolutionary information based on graph neural network and attention mechanism
Motivation: Peptides have recently emerged as promising therapeutic agents against
various diseases. For both research and safety regulation purposes, it is of high importance …
various diseases. For both research and safety regulation purposes, it is of high importance …