The role of miRNA-7 in the biology of cancer and modulation of drug resistance

E Gajda, M Grzanka, M Godlewska, D Gawel - Pharmaceuticals, 2021 - mdpi.com
MicroRNAs (miRNAs, miRs) are small non-coding RNA (ncRNA) molecules capable of
regulating post-transcriptional gene expression. Imbalances in the miRNA network have …

Metal transporter SLC39A14/ZIP14 modulates regulation between the gut microbiome and host metabolism

SB Mitchell, TL Thorn, MT Lee, Y Kim… - American Journal …, 2023 - journals.physiology.org
Metal transporter SLC39A14/ZIP14 is localized on the basolateral side of the intestine,
functioning to transport metals from blood to intestine epithelial cells. Deletion of …

Sucrose-induced hyperglycemia dysregulates intestinal zinc metabolism and integrity: risk factors for chronic diseases

SB Mitchell, YH Hung, TL Thorn, J Zou, F Baser… - Frontiers in …, 2023 - frontiersin.org
Objective Zinc is an essential micronutrient that is critical for many physiological processes,
including glucose metabolism, regulation of inflammation, and intestinal barrier function …

Integrative genome-scale analyses reveal post-transcriptional signatures of early human small intestinal development in a directed differentiation organoid model

YH Hung, M Capeling, JW Villanueva, M Kanke… - BMC genomics, 2023 - Springer
Background MicroRNAs (miRNAs) are important post-transcriptional gene regulators
controlling cellular lineage specification and differentiation during embryonic development …

A coordinated function of lncRNA HOTTIP and miRNA-196b underpinning leukemogenesis by targeting FAS signaling

AP Singh, H Luo, M Matur, MA Eshelman, K Hamamoto… - Oncogene, 2022 - nature.com
MicroRNAs (miRNAs) may modulate more than 60% of human coding genes and act as
negative regulators, whereas long noncoding RNAs (lncRNAs) regulate gene expression on …

Multiomic analysis defines the first microRNA atlas across all small intestinal epithelial lineages and reveals novel markers of almost all major cell types

MT Shanahan, M Kanke, OO Oyesola… - American Journal …, 2021 - journals.physiology.org
MicroRNA-mediated regulation is critical for the proper development and function of the
small intestinal (SI) epithelium. However, it is not known which microRNAs are expressed in …

Bioinformatic analysis of lncRNA mediated CeRNA network in intestinal ischemia/reperfusion injury

L Zhu, X Yang, Z Yao, Z Wang, Y Lai, S Xu, K Liu… - Journal of Surgical …, 2023 - Elsevier
Introduction Recently, accumulating studies have reported the roles of competitive
endogenous RNA (ceRNA) networks in ischemia/reperfusion (I/R) injury in several organs …

MicroRNA-7a2 is required for the development of pituitary stem cells

J Zhang, Y Zhou, J Guo, L Li, H Liu, C Lu… - Stem Cells and …, 2022 - liebertpub.com
The pituitary gland is inhabited by a subpopulation of SOX2+ stem cells. However, the
regulatory mechanisms underlying pituitary stem cell development remain poorly …

miR-6884-5p inhibits proliferation and epithelial-mesenchymal transition in non-small cell lung cancer cells

L Zhang, W Chi, X Wang, J Li, F Li, Y Ma, Q Zhang - Heliyon, 2024 - cell.com
Background Non-small cell lung cancer (NSCLC) is associated with a high mortality and
morbidity rate. MicroRNAs participate in tumorigenesis, progression and metastasis of …

[HTML][HTML] Intestinal stem cells heterogeneity and clonal dominance during aging: two faces of the same coin?

D Sirvinskas, F Annunziata, F Neri - Mechanisms of Ageing and …, 2020 - Elsevier
Intestinal epithelium undergoes dysfunctions and diseases over time with an exponential
increase in the elderly population. Recent studies reported that the intestinal stem cells …