Human neuronal maturation comes of age: cellular mechanisms and species differences

JL Wallace, AA Pollen - Nature Reviews Neuroscience, 2024 - nature.com
The delayed and prolonged postmitotic maturation of human neurons, compared with
neurons from other species, may contribute to human-specific cognitive abilities and …

Network state transitions during cortical development

MW Wu, N Kourdougli, C Portera-Cailliau - Nature Reviews …, 2024 - nature.com
Mammalian cortical networks are active before synaptogenesis begins in earnest, before
neuronal migration is complete, and well before an animal opens its eyes and begins to …

Specialized astrocytes mediate glutamatergic gliotransmission in the CNS

R De Ceglia, A Ledonne, DG Litvin, BL Lind, G Carriero… - Nature, 2023 - nature.com
Multimodal astrocyte–neuron communications govern brain circuitry assembly and function.
For example, through rapid glutamate release, astrocytes can control excitability, plasticity …

Molecularly targetable cell types in mouse visual cortex have distinguishable prediction error responses

SM O'Toole, HK Oyibo, GB Keller - Neuron, 2023 - cell.com
Predictive processing postulates the existence of prediction error neurons in cortex. Neurons
with both negative and positive prediction error response properties have been identified in …

Whole-cortex in situ sequencing reveals input-dependent area identity

X Chen, S Fischer, MCP Rue, A Zhang, D Mukherjee… - Nature, 2024 - nature.com
The cerebral cortex is composed of neuronal types with diverse gene expression that are
organized into specialized cortical areas. These areas, each with characteristic …

[HTML][HTML] Cortical somatostatin long-range projection neurons and interneurons exhibit divergent developmental trajectories

J Fisher, M Verhagen, Z Long, M Moissidis, Y Yan… - Neuron, 2024 - cell.com
The mammalian cerebral cortex contains an extraordinary diversity of cell types that emerge
by implementing different developmental programs. Delineating when and how cellular …

Astrocyte heterogeneity and interactions with local neural circuits

MG Holt - Essays in Biochemistry, 2023 - portlandpress.com
Astrocytes are ubiquitous within the central nervous system (CNS). These cells possess
many individual processes which extend out into the neuropil, where they interact with a …

[HTML][HTML] Synaptic gradients transform object location to action

M Dombrovski, MY Peek, JY Park, A Vaccari… - Nature, 2023 - nature.com
To survive, animals must convert sensory information into appropriate behaviours,. Vision is
a common sense for locating ethologically relevant stimuli and guiding motor responses …

Cell-type-specific inhibitory circuitry from a connectomic census of mouse visual cortex

CM Schneider-Mizell, AL Bodor, D Brittain… - …, 2024 - pmc.ncbi.nlm.nih.gov
Mammalian cortex features a vast diversity of neuronal cell types, each with characteristic
anatomical, molecular and functional properties. Synaptic connectivity powerfully shapes …

Transcriptomic cell-type specificity of local cortical circuits

M Patiño, MA Rossa, WN Lagos, NS Patne… - Neuron, 2024 - cell.com
Complex neocortical functions rely on networks of diverse excitatory and inhibitory neurons.
While local connectivity rules between major neuronal subclasses have been established …