Glycosylation is the most abundant and diverse form of post-translational modification of
proteins that is common to all eukaryotic cells. Enzymatic glycosylation of proteins involves a …

Accumulating evidence demonstrates that the oral pathobiont Fusobacterium nucleatum is
involved in the progression of an increasing number of tumors types. Thus far, the …

Sarcomas are heterogeneous and clinically challenging soft tissue and bone cancers.
Although constituting only 1% of all human malignancies, sarcomas represent the second …

Cancer mortality is exacerbated by late-stage diagnosis. Liquid biopsies based on genomic
biomarkers can noninvasively diagnose cancers. However, validation studies have …

Extracellular matrix is a highly dynamic macromolecular network. Proteoglycans are major
components of extracellular matrix playing key roles in its structural organization and cell …

Malaria remains a major public health threat in tropical and subtropical regions across the
world. Even though less than 1% of malaria infections are fatal, this leads to about 430,000 …

Prostate cancer is the most commonly diagnosed malignancy in men, claiming over 350,000
lives worldwide annually. Current diagnosis relies on prostate-specific antigen (PSA) testing …

Pancreatic cancer is a lethal condition with a rising incidence and often presents at an
advanced stage, contributing to abysmal five-year survival rates. Unspecific symptoms and …

Glycosaminoglycans (GAGs) are essential polysaccharides in normal physiology and
disease. However, understanding of the contribution of specific GAG structures to specific …

Isolation of metastatic circulating tumor cells (CTCs) from cancer patients is of high value for
disease monitoring and molecular characterization. Despite the development of many new …