Metabolic engineering: methodologies and applications

MJ Volk, VG Tran, SI Tan, S Mishra, Z Fatma… - Chemical …, 2022 - ACS Publications
Metabolic engineering aims to improve the production of economically valuable molecules
through the genetic manipulation of microbial metabolism. While the discipline is a little over …

Revisiting solar energy flow in nanomaterial-microorganism hybrid systems

J Liang, K **ao, X Wang, T Hou, C Zeng, X Gao… - Chemical …, 2024 - ACS Publications
Nanomaterial-microorganism hybrid systems (NMHSs), integrating semiconductor
nanomaterials with microorganisms, present a promising platform for broadband solar …

Upcycling CO2 into energy-rich long-chain compounds via electrochemical and metabolic engineering

T Zheng, M Zhang, L Wu, S Guo, X Liu, J Zhao… - Nature Catalysis, 2022 - nature.com
Upcycling of carbon dioxide (CO2) into value-added products represents a substantially
untapped opportunity to tackle environmental issues and achieve a circular economy …

Engineering cofactor supply and recycling to drive phenolic acid biosynthesis in yeast

R Chen, J Gao, W Yu, X Chen, X Zhai, Y Chen… - Nature Chemical …, 2022 - nature.com
Advances in synthetic biology enable microbial hosts to synthesize valuable natural
products in an efficient, cost-competitive and safe manner. However, current engineering …

Tools and strategies of systems metabolic engineering for the development of microbial cell factories for chemical production

YS Ko, JW Kim, JA Lee, T Han, GB Kim… - Chemical Society …, 2020 - pubs.rsc.org
Sustainable production of chemicals from renewable non-food biomass has become a
promising alternative to overcome environmental issues caused by our heavy dependence …

Methanol biotransformation toward high-level production of fatty acid derivatives by engineering the industrial yeast Pichia pastoris

P Cai, X Wu, J Deng, L Gao, Y Shen, L Yao… - Proceedings of the …, 2022 - pnas.org
Methanol-based biorefinery is a promising strategy to achieve carbon neutrality goals by
linking CO2 capture and solar energy storage. As a typical methylotroph, Pichia pastoris …

Rescuing yeast from cell death enables overproduction of fatty acids from sole methanol

J Gao, Y Li, W Yu, YJ Zhou - Nature Metabolism, 2022 - nature.com
Methanol is an ideal feedstock for biomanufacturing that can be beneficial for global carbon
neutrality; however, the toxicity of methanol limits the efficiency of methanol metabolism …

[HTML][HTML] What are the 100 most cited fungal genera?

CS Bhunjun, YJ Chen, C Phukhamsakda… - Studies in …, 2024 - ingentaconnect.com
The global diversity of fungi has been estimated between 2 to 11 million species, of which
only about 155 000 have been named. Most fungi are invisible to the unaided eye, but they …

Engineering co-utilization of glucose and xylose for chemical overproduction from lignocellulose

J Gao, W Yu, Y Li, M **, L Yao, YJ Zhou - Nature Chemical Biology, 2023 - nature.com
Bio-refining lignocellulose could provide a sustainable supply of fuels and fine chemicals;
however, the challenges associated with the co-utilization of xylose and glucose typically …

Synthetic biology strategies for microbial biosynthesis of plant natural products

A Cravens, J Payne, CD Smolke - Nature communications, 2019 - nature.com
Metabolic engineers endeavor to create a bio-based manufacturing industry using microbes
to produce fuels, chemicals, and medicines. Plant natural products (PNPs) are historically …