Recent advances in understanding how the microbiome can influence both the physiology
and the pathogenesis of disease in humans have highlighted the importance of gaining a …

Generalised pustular psoriasis (GPP) is a rare and severe neutrophilic skin disorder,
manifesting with acute episodes of pustulation and systemic upset. The discovery of …

Interleukin (IL)-37 is one of the few anti-inflammatory members of the predominantly pro-
inflammatory IL-1 cytokine family. IL-37 possesses alarmin-like properties [1] and exerts its …

Objective: The pleiotropic effect of hydroxy-3-methylglutaryl coenzyme A (HMG-CoA)
reductase inhibitors (statins) is responsible for potent defense against inflammatory …

Аннотация Атопический дерматит (АтД) является хроническим рецидивирующем
воспалительным заболеванием, которое сопровождается сильным зудом. Ведущим …

This electronic thesis or dissertation has been downloaded from the King’s Research Portal
at https://kclpure.kcl.ac.uk/portal Page 1 This electronic thesis or dissertation has been …