Shotgun proteomics aims to identify and quantify the thousands of proteins in complex
mixtures such as cell and tissue lysates and biological fluids. This approach uses liquid …

PatternLab for proteomics is an integrated computational environment that unifies several
previously published modules for the analysis of shotgun proteomic data. The contained …

The circadian transcriptional repressors cryptochrome 1 (Cry1) and 2 (Cry2) evolved from
photolyases, bacterial light-activated DNA repair enzymes. In this study, we report that while …

Dengue is the most prevalent human arbovirus disease worldwide. Dengue virus (DENV)
infection causes syndromes varying from self-limiting febrile illness to severe dengue …

The investigation of post-translational modifications (PTMs) represents one of the main
research focuses for the study of protein function and cell signaling. Mass spectrometry …

Currently, proteomic tools are able to establish a complete list of the most abundant proteins
present in a sample, providing the opportunity to study at high resolution the physiology of …

Proteomic workflows based on nanoLC–MS/MS data-dependent-acquisition analysis have
progressed tremendously in recent years. High-resolution and fast sequencing instruments …

Astrocytic tumors are known for their high progression capacity and high mortality rates; in
this regard, proteins correlated to prognosis can aid medical conduct. Although several …

Cellular senescence is a therapy endpoint in melanoma, and the senescence-associated
secretory phenotype (SASP) can affect tumor growth and microenvironment, influencing …

Histoplasmosis is a frequent mycosis in people living with HIV/AIDS and other
immunocompromised hosts. Histoplasmosis has high rates of mortality in these patients if …