Solid lipid nanoparticles (SLNs): an advanced drug delivery system targeting brain through BBB

MK Satapathy, TL Yen, JS Jan, RD Tang, JY Wang… - Pharmaceutics, 2021 - mdpi.com
The blood–brain barrier (BBB) plays a vital role in the protection and maintenance of
homeostasis in the brain. In this way, it is an interesting target as an interface for various …

Solid lipid nanoparticles and nanostructured lipid carriers as novel drug delivery systems: Applications, advantages and disadvantages

P Ghasemiyeh… - Research in …, 2018 - journals.lww.com
During the recent years, more attentions have been focused on lipid base drug delivery
system to overcome some limitations of conventional formulations. Among these delivery …

Functionalizing nanoparticles with biological molecules: develo** chemistries that facilitate nanotechnology

KE Sapsford, WR Algar, L Berti, KB Gemmill… - Chemical …, 2013 - ACS Publications
Bionanotechnology has now become firmly established in its own right as one of the
principle and focused subdisciplines within nanotechnology.(1-10) Bionanotechnology can …

Recent advances in lipid nanoparticle formulations with solid matrix for oral drug delivery

S Das, A Chaudhury - Aaps Pharmscitech, 2011 - Springer
Lipid nanoparticles based on solid matrix have emerged as potential drug carriers to
improve gastrointestinal (GI) absorption and oral bioavailability of several drugs, especially …

Solid lipid nanoparticles for parenteral drug delivery

SA Wissing, O Kayser, RH Müller - Advanced drug delivery reviews, 2004 - Elsevier
This review describes the use of nanoparticles based on solid lipids for the parenteral
application of drugs. Firstly, different types of nanoparticles based on solid lipids such as …

Aptamer-functionalized PEG–PLGA nanoparticles for enhanced anti-glioma drug delivery

J Guo, X Gao, L Su, H **a, G Gu, Z Pang, X Jiang… - Biomaterials, 2011 - Elsevier
Targeted delivery of therapeutic nanoparticles in a disease-specific manner represents a
potentially powerful technology especially when treating infiltrative brain tumors such as …

[HTML][HTML] Paclitaxel nano-delivery systems: a comprehensive review

P Ma, RJ Mumper - Journal of nanomedicine & nanotechnology, 2013 - ncbi.nlm.nih.gov
Paclitaxel is one of the most effective chemotherapeutic drugs ever developed and is active
against a broad range of cancers, such as lung, ovarian, and breast cancers. Due to its low …

[書籍][B] Microencapsulation: methods and industrial applications

S Benita - 2005 - taylorfrancis.com
Presenting breakthrough research pertinent to scientists in a wide range of disciplines-from
medicine and biotechnology to cosmetics and pharmacy-this Second Edition provides …

Paclitaxel-loaded PLGA nanoparticles: preparation, physicochemical characterization and in vitro anti-tumoral activity

C Fonseca, S Simoes, R Gaspar - Journal of controlled release, 2002 - Elsevier
The main objective of this study was to develop a polymeric drug delivery system for
paclitaxel, intended to be intravenously administered, capable of improving the therapeutic …

Potential of solid lipid nanoparticles in brain targeting

IP Kaur, R Bhandari, S Bhandari, V Kakkar - Journal of Controlled release, 2008 - Elsevier
Brain is a delicate organ, isolated from general circulation and characterized by the
presence of relatively impermeable endothelial cells with tight junctions, enzymatic activity …