Zwitterionic biomaterials
The term “zwitterionic polymers” refers to polymers that bear a pair of oppositely charged
groups in their repeating units. When these oppositely charged groups are equally …
groups in their repeating units. When these oppositely charged groups are equally …
Immunomodulatory biomaterials for tissue repair
R Whitaker, B Hernaez-Estrada… - Chemical …, 2021 - ACS Publications
All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …
inflammatory response was once considered a detrimental force to be blunted or avoided, in …
Biomaterials: foreign bodies or tuners for the immune response?
E Mariani, G Lisignoli, RM Borzì… - International journal of …, 2019 - mdpi.com
The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …
to biomaterial implantation, despite the robustness of technologies that hold the promise to …
Zwitterionic hydrogels implanted in mice resist the foreign-body reaction
The performance of implantable biomedical devices is impeded by the foreign-body
reaction, which results in formation of a dense collagenous capsule that blocks mass …
reaction, which results in formation of a dense collagenous capsule that blocks mass …
[HTML][HTML] Modulating the immune system towards a functional chronic wound healing: A biomaterials and Nanomedicine perspective
Chronic non-healing wounds persist as a substantial burden for healthcare systems,
influenced by factors such as aging, diabetes, and obesity. In contrast to the traditionally pro …
influenced by factors such as aging, diabetes, and obesity. In contrast to the traditionally pro …
Extracellular matrix-based biomaterial scaffolds and the host response
JM Aamodt, DW Grainger - Biomaterials, 2016 - Elsevier
Extracellular matrix (ECM) collectively represents a class of naturally derived proteinaceous
biomaterials purified from harvested organs and tissues with increasing scientific focus and …
biomaterials purified from harvested organs and tissues with increasing scientific focus and …
Monocytes and macrophages in tissue repair: Implications for immunoregenerative biomaterial design
ME Ogle, CE Segar, S Sridhar… - … Biology and Medicine, 2016 - journals.sagepub.com
Monocytes and macrophages play a critical role in tissue development, homeostasis, and
injury repair. These innate immune cells participate in guiding vascular remodeling …
injury repair. These innate immune cells participate in guiding vascular remodeling …
[HTML][HTML] The effects of substrate stiffness on the in vitro activation of macrophages and in vivo host response to poly (ethylene glycol)-based hydrogels
Abstract Poly (ethylene glycol)(PEG) hydrogels, modified with RGD, are promising platforms
for cell encapsulation and tissue engineering. While these hydrogels offer tunable …
for cell encapsulation and tissue engineering. While these hydrogels offer tunable …
Biomaterials for cell transplantation
Cell transplantation holds immense potential for reversing diseases that are currently
incurable and for regenerating tissues. However, poor cell survival, cell aggregation and …
incurable and for regenerating tissues. However, poor cell survival, cell aggregation and …
Zwitterionic polymers and hydrogels for antibiofouling applications in implantable devices
Biofouling, generally initiated by non-specific adsorption of cells, proteins and
microorganisms, is a persistent challenge in a wide range of applications, including …
microorganisms, is a persistent challenge in a wide range of applications, including …