Berberine as a potential anticancer agent: A comprehensive review

A Rauf, T Abu-Izneid, AA Khalil, M Imran, ZA Shah… - Molecules, 2021 - mdpi.com
Berberine (BBR), a potential bioactive agent, has remarkable health benefits. A substantial
amount of research has been conducted to date to establish the anticancer potential of BBR …

Ethnobotany and the role of plant natural products in antibiotic drug discovery

G Porras, F Chassagne, JT Lyles, L Marquez… - Chemical …, 2020 - ACS Publications
The crisis of antibiotic resistance necessitates creative and innovative approaches, from
chemical identification and analysis to the assessment of bioactivity. Plant natural products …

Gut microbiome-related effects of berberine and probiotics on type 2 diabetes (the PREMOTE study)

Y Zhang, Y Gu, H Ren, S Wang, H Zhong… - Nature …, 2020 - nature.com
Human gut microbiome is a promising target for managing type 2 diabetes (T2D). Measures
altering gut microbiota like oral intake of probiotics or berberine (BBR), a bacteriostatic …

Plant isoquinoline alkaloids: Advances in the chemistry and biology of berberine

S Singh, N Pathak, E Fatima, AS Negi - European Journal of Medicinal …, 2021 - Elsevier
Alkaloids are one of the most important classes of plant bioactives. Among these
isoquinoline alkaloids possess varied structures and exhibit numerous biological activities …

[HTML][HTML] Berberine in cardiovascular and metabolic diseases: from mechanisms to therapeutics

X Feng, A Sureda, S Jafari, Z Memariani, D Tewari… - Theranostics, 2019 - ncbi.nlm.nih.gov
Cardiovascular and metabolic diseases (CVMD) are the leading causes of death worldwide,
underscoring the urgent necessity to develop new pharmacotherapies. Berberine (BBR) is …

Berberine and barberry (Berberis vulgaris): A clinical review

M Imenshahidi, H Hosseinzadeh - Phytotherapy Research, 2019 - Wiley Online Library
Barberry (Berberis vulgaris L.) has different medicinal applications in folk medicine of Iran.
Berberine, an alkaloid constituent of this plant, is present in the roots, rhizomes, stem, and …

[HTML][HTML] Therapeutic effect of berberine on metabolic diseases: Both pharmacological data and clinical evidence

X Xu, H Yi, J Wu, T Kuang, J Zhang, Q Li, H Du… - Biomedicine & …, 2021 - Elsevier
The increased incidence of metabolic diseases (eg, diabetes and obesity) has seriously
affected human health and life safety worldwide. It is of great significance to find effective …

[HTML][HTML] Berberine ameliorates DSS-induced intestinal mucosal barrier dysfunction through microbiota-dependence and Wnt/β-catenin pathway

Y Dong, H Fan, Z Zhang, F Jiang, M Li… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disorder of the colon, and it has
become one of the world-recognized medical problems as it is recurrent and refractory …

Berberine improves colitis by triggering AhR activation by microbial tryptophan catabolites

W **g, S Dong, X Luo, J Liu, B Wei, W Du… - Pharmacological …, 2021 - Elsevier
Inflammatory bowel diseases (IBD) are kind of recurrent inflammatory issues that occur in
the gastrointestinal tract, and currently clinical treatment is still unideal due to the complex …

Anticancer effects and mechanisms of berberine from medicinal herbs: An update review

RG **ong, SY Huang, SX Wu, DD Zhou, ZJ Yang… - Molecules, 2022 - mdpi.com
Cancer has been a serious public health problem. Berberine is a famous natural compound
from medicinal herbs and shows many bioactivities, such as antioxidant, anti-inflammatory …