The versatile, changing, and advancing roles of fish in sediment toxicity assessment—a review

AV Hallare, TB Seiler, H Hollert - Journal of Soils and Sediments, 2011 - Springer
Purpose Sediments serve as integral and dynamic parts of our aquatic systems. Within the
last 15 to 20 years, however, the scientific community has begun noticing deterioration of …

The value of zebrafish as an integrative model in effect-directed analysis-a review

C Di Paolo, TB Seiler, S Keiter, M Hu, M Muz… - Environmental Sciences …, 2015 - Springer
Bioassays play a central role in effect-directed analysis (EDA), and their selection and
application have to consider rather specific aspects of this approach. Meanwhile, bioassays …

A novel contact assay for testing aryl hydrocarbon receptor (AhR)-mediated toxicity of chemicals and whole sediments in zebrafish (Danio rerio) embryos

S Schiwy, J Bräunig, H Alert, H Hollert… - … Science and Pollution …, 2015 - Springer
Abstract The European Water Framework Directive aims to achieve a good ecological and
chemical status in surface waters until 2015. Sediment toxicology plays a major role in this …

Metal contamination in sediments of dam reservoirs: A multi-facetted generic risk assessment

A Baran, FMG Tack, A Delemazure, J Wieczorek… - Chemosphere, 2023 - Elsevier
The quality of bottom sediments is a key factor for many functions of dam reservoirs, which
include water supply, flood control and recreation. The aim of the study was to combine …

Acetylcholinesterase in zebrafish embryos as a tool to identify neurotoxic effects in sediments

B Kais, D Stengel, A Batel, T Braunbeck - Environmental Science and …, 2015 - Springer
In order to clarify the suitability of zebrafish (Danio rerio) embryos for the detection of
neurotoxic compounds, the acetylcholinesterase assay was adapted and validated with a …

In vivo EROD assays with the zebrafish (Danio rerio) as rapid screening tools for the detection of dioxin-like activity

B Kais, S Schiwy, H Hollert, SH Keiter… - Science of the Total …, 2017 - Elsevier
The present study compares two alternative in vivo approaches for the measurement of
ethoxyresorufin-O-deethylase (EROD) activity in zebrafish (Danio rerio) following exposure …

Time-dependent expression and activity of cytochrome P450 1s in early life-stages of the zebrafish (Danio rerio)

J Bräunig, S Schiwy, O Broedel, Y Müller… - … Science and Pollution …, 2015 - Springer
Zebrafish embryos are being increasingly used as model organisms for the assessment of
single substances and complex environmental samples for regulatory purposes. Thus, it is …

Toxicity and neurotoxicity profiling of contaminated sediments from Gulf of Bothnia (Sweden): a multi-endpoint assay with Zebrafish embryos

R Massei, H Hollert, M Krauss, W Von Tümpling… - Environmental Sciences …, 2019 - Springer
Background The toxicological characterization of sediments is an essential task to monitor
the quality of aquatic environments. Many hazardous pollutants may accumulate in …

Danio rerio as a model in aquatic toxicology and sediment research

H Hollert, SH Keiter - Environmental Science and Pollution Research, 2015 - Springer
Worldwide, the zebrafish (Danio rerio) has become a prominent model for biomedical
research and (eco) toxicology (Strähle et al. 2012). Within favourable conditions, female fish …

Morphological and behavioral alterations in zebrafish larvae after exposure to contaminated river sediments collected in different weather conditions

A Shuliakevich, K Schröder, L Nagengast… - Science of the Total …, 2022 - Elsevier
Wastewater treatment plants (WWTPs) are the primary source of micropollutants in aquatic
ecosystems. Many micropollutants tend to bind to sediments and persist until remobilizion by …