Recently, deep learning (DL) approaches have become the main research frontier for
biological image reconstruction and enhancement problems thanks to their high …

Single-particle cryo-electron microscopy (cryo-EM) is a technique that takes projection
images of biomolecules frozen at cryogenic temperatures. A major advantage of this …

Macromolecules change their shape (conformation) in the process of carrying out their
functions. The imaging by cryo-electron microscopy of rapidly-frozen, individual copies of …

Cryo-electron microscopy (CryoEM) has become a vital technique in structural biology. It is
an interdisciplinary field that takes advantage of advances in biochemistry, physics, and …

Single-particle cryo-electron microscopy (cryo-EM) is a technique for biomolecular structure
reconstruction from vitrified samples containing many copies of a biomolecular complex …

Physics-informed generative modeling for inverse problems in computational imaging is a
fast-growing field encompassing a variety of methods and applications. Here, we review a …

Advances in cryo-electron microscopy (cryo-EM) for high-resolution imaging of biomolecules
in solution have provided new challenges and opportunities for algorithm development for …

Solving an ill-posed linear inverse problem requires knowledge about the underlying signal
model. In many applications, this model is a priori unknown and has to be learned from data …

Cryogenic electron microscopy (cryo-EM) provides im-ages from different copies of the same
biomolecule in ar-bitrary orientations. Here, we present an end-to-end unsu-pervised …

Biological macromolecules and assemblies precisely rearrange their atomic 3D structures to
execute cellular functions. Understanding the mechanisms by which these molecular …