Troponin is a heterotrimeric Ca2+-binding protein that has a well-established role in
regulating striated muscle contraction. However, mounting evidence points to novel cellular …

The troponin complex—consisting of three subunits: troponin C (TnC), cardiac troponin I
(cTnI) and cardiac troponin T (cTnT)—plays a key role in the regulation of myocardial …

Glioblastoma (GB) is the most aggressive, lethal and frequent primary brain tumor. It
originates from glial cells and is characterized by rapid expansion through infiltration. GB …

In our previous study, intranuclear cardiac troponin I (cTnI) may function as a co‐factor of Yin
Yang 1 (YY1). Here, we aimed to explore the role of intranuclear cTnI in ageing hearts …

HDAC4 is a potent memory repressor with overexpression of wild type or a nuclear-
restricted mutant resulting in memory deficits. Interestingly, reduction of HDAC4 also impairs …

Several bacteria of environmental and clinical origins, including some human-associated
strains secrete a cross-kingdom signaling molecule indole-3-acetic acid (IAA). IAA is a …

In this study, we describe a novel function of TNNC1 (Troponin C1, Slow Skeletal and
Cardiac Type), a component of actin-bound troponin, as a tumor suppressor of lung …

In the past studies, it is shown that cardiac troponin I (cTnI, encoded by TNNI3), as a
cytoplasmic protein, is an inhibitory subunit in troponin complex, and involves in …

Background Ageing skeletal muscle undergoes chronic denervation, and the neuromuscular
junction (NMJ), the key structure that connects motor neuron nerves with muscle cells …

Cardiac troponin I (cTnI) is the only sarcomeric protein identified to date that is expressed
exclusively in cardiac muscle. Its expression in cancer tissues has not been reported …