Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …

Evolution is the hallmark of life. Descriptions of the evolution of microorganisms have
provided a wealth of information, but knowledge regarding “what happened” has precluded …

Antibiotics can exert selective pressures on sludge as well as affect the emergence and
spread of antibiotic resistance genes (ARGs). However, the underlying mechanisms of …

Bacteria possess a diverse range of mechanisms for inhibiting competitors, including
bacteriocins, tailocins, type VI secretion systems and contact-dependent inhibition (CDI) …

Competition between microbes is extremely common, with many investing in mechanisms to
harm other strains and species. Yet positive interactions between species have also been …

Antimicrobial resistance (AMR) with the ability to thwart clinical therapies and escalate
mortality rates is emerging as one of the most pressing global health and environmental …

The efficacy of antibiotic treatments targeting polymicrobial communities is not well predicted
by conventional in vitro susceptibility testing based on determining minimum inhibitory …

Niche Theory is a central framework in ecology based on the recognition that most
interactions between organisms are indirect, mediated by the biotic and abiotic dynamical …

The remarkable impact of antibiotics on human health is being eroded at an alarming rate by
the emergence of multidrug resistant pathogens. There is a recognised consensus that new …

Despite the increasing number of effective anti-cancer therapies, successful treatment is
limited by the development of drug resistance. While the contribution of genetic factors to …