Evolutionary divergence of embryo implantation in primates

D Siriwardena, TE Boroviak - … Transactions of the …, 2022 - royalsocietypublishing.org
Implantation of the conceptus into the uterus is absolutely essential for successful embryo
development. In humans, our understanding of this process has remained rudimentary …

Understanding the mechanobiology of early mammalian development through bioengineered models

S Vianello, MP Lutolf - Developmental cell, 2019 - cell.com
Research in developmental biology has been recently enriched by a multitude of in vitro
models recapitulating key milestones of mammalian embryogenesis. These models obviate …

Integrated systems biology approach identifies novel maternal and placental pathways of preeclampsia

NG Than, R Romero, AL Tarca, KA Kekesi… - Frontiers in …, 2018 - frontiersin.org
Preeclampsia is a disease of the mother, fetus, and placenta, and the gaps in our
understanding of the complex interactions among their respective disease pathways …

Three-dimensional microengineered vascularised endometrium-on-a-chip

J Ahn, MJ Yoon, SH Hong, H Cha, D Lee… - Human …, 2021 - academic.oup.com
STUDY QUESTION Can we reconstitute physiologically relevant 3-dimensional (3D)
microengineered endometrium in-vitro model? SUMMARY ANSWER Our representative …

Pregnancy-related extracellular vesicles revisited

CE Condrat, VN Varlas, F Duică, P Antoniadis… - International journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) are small vesicles ranging from 20–200 nm to 10 μm in diameter
that are discharged and taken in by many different types of cells. Depending on the nature …

[HTML][HTML] Melatonin, its beneficial effects on embryogenesis from mitigating oxidative stress to regulating gene expression

D Ivanov, G Mazzoccoli, G Anderson… - International journal of …, 2021 - mdpi.com
Embryogenesis is a complex multi-stage process regulated by various signaling molecules
including pineal and extrapineal melatonin (MT). Extrapineal MT is found in the placenta …

Insights into the regulation of implantation and placentation in humans, rodents, sheep, and pigs

C Stenhouse, H Seo, G Wu, GA Johnson… - Recent advances in …, 2022 - Springer
Precise cell-specific spatio-temporal molecular signaling cascades regulate the
establishment and maintenance of pregnancy. Importantly, the mechanisms regulating …

Norflurazon causes cell death and inhibits implantation-related genes in porcine trophectoderm and uterine luminal epithelial cells

T Hong, S Park, G An, FW Bazer, G Song… - Food and Chemical …, 2024 - Elsevier
Norflurazon, an inhibitor of carotenoid synthesis, is a pre-emergent herbicide that prevents
growth of weeds. The norflurazon is known to hamper embryo development in non …

Dinitramine induces implantation failure by cell cycle arrest and mitochondrial dysfunction in porcine trophectoderm and luminal epithelial cells

J Park, G An, W Lim, G Song - Journal of hazardous materials, 2022 - Elsevier
The herbicide market is growing rapidly, as weed control is a significant challenge in
agriculture. Many studies have reported the toxicity of herbicides to non-target organisms …