Pathogens manipulate the cellular mechanisms of host organisms via pathogen–host
interactions (PHIs) in order to take advantage of the capabilities of host cells, leading to …

Gene regulatory network inference is a systems biology approach which predicts
interactions between genes with the help of high-throughput data. In this review, we present …

The ability to adapt to diverse micro-environmental challenges encountered within a host is
of pivotal importance to the opportunistic fungal pathogen Candida albicans. We have …

Mitogen activated protein kinases (MAPKs) are highly conserved in eukaryotic organisms. In
pathogenic fungi, their activities were assigned to different physiological functions including …

Inference of inter-species gene regulatory networks based on gene expression data is an
important computational method to predict pathogen-host interactions (PHIs). Both the …

Elucidation of pathogenicity mechanisms of the most important human-pathogenic fungi,
Aspergillus fumigatus and Candida albicans, has gained great interest in the light of the …

Nitrogen is one of the key nutrients for microbial growth. During infection, pathogenic fungi
like C. albicans need to acquire nitrogen from a broad range of different and changing …

Using Botrytis cinerea we confirmed in the present work several previous studies showing
that salicylic acid, a main plant hormone, inhibits fungal growth in vitro. Such an inhibitory …

Intestinal epithelial cells (IEC) form a tight barrier to the gut lumen. Paracellular permeability
of the intestinal barrier is regulated by tight junction proteins and can be modulated by …

Candida albicans is an opportunist pathogen responsible for a large spectrum of infections,
from superficial mycosis to systemic diseases known as candidiasis. Its ability to grow in …