Pressures between 10 and 100 MPa can exert powerful effects on the growth and viability of
organisms. Here I describe the effects of elevated pressure in this range on mesophilic …

The initiation of replication is the central event in the bacterial cell cycle. Cells control the
rate of DNA synthesis by modulating the frequency with which new chains are initiated, like …

The Escherichia coli SeqA protein contributes to regulation of chromosome replication by
preventing re-initiation at newly replicated origins. SeqA protein binds to new DNA which is …

Since bacteria in foods often encounter various cold environments during food processing,
such as chilling, cold chain distribution, and cold storage, lower temperatures can become a …

Microorganisms adapted to piezopsychrophilic growth dominate the majority of the
biosphere that is at relatively constant low temperatures and high pressures, but the genetic …

Publisher Summary This chapter discusses recent discoveries in this field, with special
emphasis on molecular systems operating to sense the current status of the host physiology …

Caulobacter crescentus chromosome replication is precisely coupled to a developmental
cell cycle. Like most eubacteria, C. crescentus has a DnaA homologue that is presumed to …

DnaA initiates chromosomal replication in Escherichia coli at a well‐regulated time in the
cell cycle. To determine how the spatial distribution of DnaA is related to the location of …

DNA replication in Escherichia coli is controlled at the initiation stage, possibly by regulation
of the essential activity of DnaA protein. The cellular membrane has long been hypothesized …

The importance of the cell membrane in bacterial chromosomal replication continues to
emerge. Recent advances include better definition of the biochemical interaction between …