AI-Enhanced RAIN Protocol: A Systematic Approach to Optimize Drug Combinations for Rectal Neoplasm Treatment

N Dashti, AA Kiaei, M Boush, B Gholami-Borujeni… - bioRxiv, 2024‏ - biorxiv.org
Background Rectal cancers, or rectal neoplasms, are tumors that develop from the lining of
the rectum, the concluding part of the large intestine ending at the anus. These tumors often …

Neoadjuvant chemoradiotherapy in combination with deep regional hyperthermia followed by surgery for rectal cancer: a systematic review and meta-analysis

A Ademaj, S Stieb, C Gani, OJ Ott, D Marder… - Strahlentherapie und …, 2025‏ - Springer
Background and purpose Combining chemoradiotherapy (CRT) with deep regional
hyperthermia (HT) shows promise for enhancing clinical outcomes in selected rectal cancer …

Short-term and long-term oncological outcomes of chemoradiotherapy for rectal cancer patients with or without oxaliplatin: a propensity score-matched retrospective …

A Azimi, FS Tabatabaei, K Kolahdouzan… - Radiation …, 2024‏ - Springer
Current approaches for locally advanced rectal cancer (LARC) typically recommend
neoadjuvant chemoradiotherapy (nCRT) with 5-fluorouracil (5FU) or its oral analogs …