Global burden of hepatitis B virus: current status, missed opportunities and a call for action

YC Hsu, DQ Huang, MH Nguyen - Nature reviews Gastroenterology & …, 2023 - nature.com
Chronic hepatitis B virus (HBV) infection affects about 296 million people worldwide and is
the leading aetiology of cirrhosis and liver cancer globally. Major medical complications also …

A roadmap for serum biomarkers for hepatitis B virus: current status and future outlook

A Kramvis, KM Chang, M Dandri, P Farci… - Nature Reviews …, 2022 - nature.com
Globally, 296 million people are infected with hepatitis B virus (HBV), and approximately one
million people die annually from HBV-related causes, including liver cancer. Although there …

Hepatitis virus and hepatocellular carcinoma: recent advances

C Shen, X Jiang, M Li, Y Luo - Cancers, 2023 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is a global health challenge. Hepatitis
virus infection (including HBV, HCV and HDV) is one of the major risk factors for HCC …

Droplet digital PCR of viral‎ DNA/RNA, current progress, challenges, and future perspectives

AA Kojabad, M Farzanehpour… - Journal of Medical …, 2021 - Wiley Online Library
High‐throughput droplet‐based digital PCR (ddPCR) is a refinement of the conventional
polymerase chain reaction (PCR)‎ methods. In ddPCR, DNA/RNA is encapsulated …

Guidance for design and endpoints of clinical trials in chronic hepatitis B—report from the 2019 EASL‐AASLD HBV Treatment Endpoints Conference

M Cornberg, ASF Lok, NA Terrault, F Zoulim - Hepatology, 2020 - journals.lww.com
Representatives from academia, industry, regulatory agencies, and patient groups
convened in March 2019 with the primary goal of develo** agreement on chronic hepatitis …

KASL clinical practice guidelines for management of chronic hepatitis B

Korean Association for the Study of the … - Clinical and …, 2019 - pmc.ncbi.nlm.nih.gov
Diseases (AASLD) also presented and continued to revise their clinical practice guidelines,
and the latest updates were in 2015, 2017, and 2018. However, since the medical …

Occult hepatitis B infection and hepatocellular carcinoma: Epidemiology, virology, hepatocarcinogenesis and clinical significance

LY Mak, DKH Wong, T Pollicino, G Raimondo… - Journal of …, 2020 - Elsevier
Occult hepatitis B infection (OBI) refers to a condition where replication-competent HBV DNA
is present in the liver, with or without HBV DNA in the blood, in individuals with serum …

Hepatitis B virus persistence and reactivation

Y Shi, M Zheng - Bmj, 2020 - bmj.com
Hepatitis B virus (HBV) infection causes chronic hepatitis and has long term complications.
Individuals ever infected with HBV are at risk of viral reactivation under certain …

Occult hepatitis B virus infection: an update

C Saitta, T Pollicino, G Raimondo - Viruses, 2022 - mdpi.com
Occult hepatitis B virus (HBV) infection (OBI) refers to a condition in which replication-
competent viral DNA is present in the liver (with detectable or undetectable HBV DNA in the …

The evolution and clinical impact of hepatitis B virus genome diversity

PA Revill, T Tu, HJ Netter, LKW Yuen… - Nature Reviews …, 2020 - nature.com
The global burden of hepatitis B virus (HBV) is enormous, with 257 million persons
chronically infected, resulting in more than 880,000 deaths per year worldwide. HBV exists …