ATP-binding cassette (ABC) transporters constitute one of the largest and most ancient
protein superfamilies found in all living organisms. They function as molecular machines by …

Success in nature depends upon an ability to perceive and adapt to the surrounding
environment. Bacteria are not an exception; they recognize and constantly adjust to …

ATP-binding cassette (ABC) transporters form a large superfamily of ATP-dependent protein
complexes that mediate transport of a vast array of substrates across membranes. The 14 …

Currently optical-based techniques for in vivo microbial population imaging are limited by
low imaging depth and highly light-scattering tissue; and moreover, are generally effective …

Simultaneous imaging and treatment of infections remains a major challenge, with most
current approaches being effective against only one specific group of bacteria or not being …

Glucose arguably is the most important energy carrier, carbon source for metabolites and
building block for biopolymers in all kingdoms of life. The proper function of animal organs …

Infectious diseases caused by pathogenic bacteria, especially antibiotic-resistant bacteria,
are one of the biggest threats to global health. To date, bacterial contamination is detected …

Most existing bioluminescence imaging methods can only visualize the location of
engineered bacteria in vivo, generally precluding the imaging of natural bacteria. Herein, we …

Current vehicles used to deliver antisense oligonucleotides (ASOs) cannot distinguish
between bacterial and mammalian cells, greatly hindering the preclinical or clinical …

ATP-binding cassette (ABC) transporters use the energy of ATP hydrolysis to transport a
large diversity of molecules actively across biological membranes. A combination of …