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Astrocyte‐mediated mechanisms contribute to traumatic brain injury pathology
Astrocytes respond to traumatic brain injury (TBI) with changes to their molecular make‐up
and cell biology, which results in changes in astrocyte function. These changes can be …
and cell biology, which results in changes in astrocyte function. These changes can be …
Context is key: glucocorticoid receptor and corticosteroid therapeutics in outcomes after traumatic brain injury
Traumatic brain injury (TBI) is a global health burden, and survivors suffer functional and
psychiatric consequences that can persist long after injury. TBI induces a physiological …
psychiatric consequences that can persist long after injury. TBI induces a physiological …
Pathophysiology of pediatric traumatic brain injury
The national incidence of traumatic brain injury (TBI) exceeds that of any other disease in
the pediatric population. In the United States the Centers for Disease Control and Prevention …
the pediatric population. In the United States the Centers for Disease Control and Prevention …
[HTML][HTML] An overview of mild traumatic brain injuries and emerging therapeutic targets
The majority of traumatic brain injuries (TBIs), approximately 90%, are classified as mild
(mTBIs). Globally, an estimated 4 million injuries occur each year from concussions or …
(mTBIs). Globally, an estimated 4 million injuries occur each year from concussions or …
[HTML][HTML] Stress and traumatic brain injury: An inherent bi-directional relationship with temporal and synergistic complexities
Traumatic brain injury (TBI) and stress are prevalent worldwide and can both result in life-
altering health problems. While stress often occurs in the absence of TBI, TBI inherently …
altering health problems. While stress often occurs in the absence of TBI, TBI inherently …
Timing matters: Sex differences in inflammatory and behavioral outcomes following repetitive blast mild traumatic brain injury
Background Repetitive blast-related mild traumatic brain injury (mTBI) caused by exposure
to high explosives is increasingly common among warfighters as well as civilians. While …
to high explosives is increasingly common among warfighters as well as civilians. While …
[HTML][HTML] The role of the stress system in recovery after traumatic brain injury: a tribute to Bruce S. McEwen
Traumatic brain injury (TBI) represents a major public health concern. Although the majority
of individuals that suffer mild-moderate TBI recover relatively quickly, a substantial subset of …
of individuals that suffer mild-moderate TBI recover relatively quickly, a substantial subset of …
Bidirectional brain-systemic interactions and outcomes after TBI
Traumatic brain injury (TBI) is a debilitating disorder associated with chronic progressive
neurodegeneration and long-term neurological decline. Importantly, there is now substantial …
neurodegeneration and long-term neurological decline. Importantly, there is now substantial …
Satureja khuzistanica Jamzad essential oil and pure carvacrol attenuate TBI-induced inflammation and apoptosis via NF-κB and caspase-3 regulation in the male rat …
E Abbasloo, S Amiresmaili, S Shirazpour… - Scientific Reports, 2023 - nature.com
Traumatic brain injury (TBI) causes progressive dysfunction that induces biochemical and
metabolic changes that lead to cell death. Nevertheless, there is no definitive FDA-approved …
metabolic changes that lead to cell death. Nevertheless, there is no definitive FDA-approved …
[HTML][HTML] Drosophila as a model to explore secondary injury cascades after traumatic brain injury
Drosophilae are emerging as a valuable model to study traumatic brain injury (TBI)-induced
secondary injury cascades that drive persisting neuroinflammation and neurodegenerative …
secondary injury cascades that drive persisting neuroinflammation and neurodegenerative …