Astrocyte‐mediated mechanisms contribute to traumatic brain injury pathology

C Muñoz‐Ballester, S Robel - WIREs mechanisms of disease, 2023 - Wiley Online Library
Astrocytes respond to traumatic brain injury (TBI) with changes to their molecular make‐up
and cell biology, which results in changes in astrocyte function. These changes can be …

Context is key: glucocorticoid receptor and corticosteroid therapeutics in outcomes after traumatic brain injury

MA Taylor, ON Kokiko-Cochran - Frontiers in Cellular Neuroscience, 2024 - frontiersin.org
Traumatic brain injury (TBI) is a global health burden, and survivors suffer functional and
psychiatric consequences that can persist long after injury. TBI induces a physiological …

Pathophysiology of pediatric traumatic brain injury

RO Serpa, L Ferguson, C Larson, J Bailard… - Frontiers in …, 2021 - frontiersin.org
The national incidence of traumatic brain injury (TBI) exceeds that of any other disease in
the pediatric population. In the United States the Centers for Disease Control and Prevention …

[HTML][HTML] An overview of mild traumatic brain injuries and emerging therapeutic targets

JP Bielanin, SAH Metwally, SS Paruchuri… - Neurochemistry …, 2024 - Elsevier
The majority of traumatic brain injuries (TBIs), approximately 90%, are classified as mild
(mTBIs). Globally, an estimated 4 million injuries occur each year from concussions or …

[HTML][HTML] Stress and traumatic brain injury: An inherent bi-directional relationship with temporal and synergistic complexities

J Brand, SJ McDonald, JR Gawryluk, BR Christie… - Neuroscience & …, 2023 - Elsevier
Traumatic brain injury (TBI) and stress are prevalent worldwide and can both result in life-
altering health problems. While stress often occurs in the absence of TBI, TBI inherently …

Timing matters: Sex differences in inflammatory and behavioral outcomes following repetitive blast mild traumatic brain injury

BM Baskin, AF Logsdon, SJ Lee, BD Foresi… - Brain, behavior, and …, 2023 - Elsevier
Background Repetitive blast-related mild traumatic brain injury (mTBI) caused by exposure
to high explosives is increasingly common among warfighters as well as civilians. While …

[HTML][HTML] The role of the stress system in recovery after traumatic brain injury: a tribute to Bruce S. McEwen

ZM Weil, B White, B Whitehead, K Karelina - Neurobiology of Stress, 2022 - Elsevier
Traumatic brain injury (TBI) represents a major public health concern. Although the majority
of individuals that suffer mild-moderate TBI recover relatively quickly, a substantial subset of …

Bidirectional brain-systemic interactions and outcomes after TBI

AI Faden, JP Barrett, BA Stoica, RJ Henry - Trends in neurosciences, 2021 - cell.com
Traumatic brain injury (TBI) is a debilitating disorder associated with chronic progressive
neurodegeneration and long-term neurological decline. Importantly, there is now substantial …

Satureja khuzistanica Jamzad essential oil and pure carvacrol attenuate TBI-induced inflammation and apoptosis via NF-κB and caspase-3 regulation in the male rat …

E Abbasloo, S Amiresmaili, S Shirazpour… - Scientific Reports, 2023 - nature.com
Traumatic brain injury (TBI) causes progressive dysfunction that induces biochemical and
metabolic changes that lead to cell death. Nevertheless, there is no definitive FDA-approved …

[HTML][HTML] Drosophila as a model to explore secondary injury cascades after traumatic brain injury

LM Buhlman, G Krishna, TB Jones… - Biomedicine & …, 2021 - Elsevier
Drosophilae are emerging as a valuable model to study traumatic brain injury (TBI)-induced
secondary injury cascades that drive persisting neuroinflammation and neurodegenerative …