Transient or permanent loss of tissue perfusion due to ischaemic stroke can lead to damage
to the neurovasculature, and disrupt brain homeostasis, causing long-term motor and …

Ischemic stroke, which is the second highest cause of death and the leading cause of
disability, represents~ 71% of all strokes globally. Some studies have found that the key …

Oxidative stress and a series of excessive inflammatory responses are major obstacles for
neurological functional recovery after ischemic stroke. Effective noninvasive anti …

Importance Preclinical and clinical studies have suggested a neuroprotective effect of
remote ischemic conditioning (RIC), which involves repeated occlusion/release cycles on …

Stroke is the leading neurological cause of death and disability all over the world, with few
effective drugs. Nerve growth factor (NGF) is well known for its multifaceted neuroprotective …

Astrocyte-mediated inflammation and oxidative stress elicit cerebral ischemia-reperfusion
(IR) injury after stroke. Nuclear factor (NF)-κB activates astrocytes and generates pro …

Endoplasmic reticulum (ER) is the main organelle for protein synthesis, trafficking and
maintaining intracellular Ca2+ homeostasis. The stress response of ER results from the …

Western medicine is routinely used in developed nations as well as in Eastern countries,
where traditional medicine is frequently used by a selection of patients or family member as …

Endogenous neurogenesis holds promise for brain repair and long‐term functional recovery
after ischaemic stroke. However, the effects of exosomes from human urine‐derived stem …

In this retrospective, multicentre, observational cohort study, we sought to determine the
clinical, radiological, EEG, genetics and neuropathological characteristics of mitochondrial …