Nanotechnology for multimodal synergistic cancer therapy

W Fan, B Yung, P Huang, X Chen - Chemical reviews, 2017‏ - ACS Publications
The complexity, diversity, and heterogeneity of tumors seriously undermine the therapeutic
potential of treatment. Therefore, the current trend in clinical research has gradually shifted …

Cancer treatment through nanoparticle-facilitated fenton reaction

H Ranji-Burachaloo, PA Gurr, DE Dunstan, GG Qiao - ACS nano, 2018‏ - ACS Publications
Currently, cancer is the second largest cause of death worldwide and has reached critical
levels. In spite of all the efforts, common treatments including chemotherapy, photodynamic …

Polymeric nanostructured materials for biomedical applications

Z Tang, C He, H Tian, J Ding, BS Hsiao, B Chu… - Progress in Polymer …, 2016‏ - Elsevier
Polymeric nanostructured materials (PNMs), which are polymeric materials in nanoscale or
polymer composites containing nanomaterials, have become increasingly useful for …

Recent advances in nanoparticle-based cancer drug and gene delivery

N Amreddy, A Babu, R Muralidharan… - Advances in cancer …, 2018‏ - Elsevier
Effective and safe delivery of anticancer agents is among the major challenges in cancer
therapy. The majority of anticancer agents are toxic to normal cells, have poor bioavailability …

Synergistic nanomedicine by combined gene and photothermal therapy

J Kim, J Kim, C Jeong, WJ Kim - Advanced drug delivery reviews, 2016‏ - Elsevier
To date, various nanomaterials with the ability for gene delivery or photothermal effect have
been developed in the field of biomedicine. The therapeutic potential of these nanomaterials …

Co-delivery of siRNAs and anti-cancer drugs using layered double hydroxide nanoparticles

L Li, W Gu, J Chen, W Chen, ZP Xu - Biomaterials, 2014‏ - Elsevier
In this research we employed layered double hydroxide nanoparticles (LDHs) to
simultaneously deliver an anticancer drug 5-fluorouracil (5-FU) and Allstars Cell Death …

Co-delivery of drugs and plasmid DNA for cancer therapy

PY Teo, W Cheng, JL Hedrick, YY Yang - Advanced drug delivery reviews, 2016‏ - Elsevier
Cancer is an extremely complex disease involving multiple signaling pathways that enable
tumor cells to evade programmed cell death, thus making cancer treatment extremely …

Aptamer-functionalized DNA origami for targeted codelivery of antisense oligonucleotides and doxorubicin to enhance therapy in drug-resistant cancer cells

Q Pan, C Nie, Y Hu, J Yi, C Liu, J Zhang… - … Applied Materials & …, 2019‏ - ACS Publications
Drug resistance is a major obstacle to the efficient therapy of drug-resistant cancer. To
overcome this problem, we constructed a multifunctional DNA origami-based nanocarrier for …

3D printed polycaprolactone carbon nanotube composite scaffolds for cardiac tissue engineering

CMB Ho, A Mishra, PTP Lin, SH Ng… - Macromolecular …, 2017‏ - Wiley Online Library
Fabrication of tissue engineering scaffolds with the use of novel 3D printing has gained lot of
attention, however systematic investigation of biomaterials for 3D printing have not been …

Dual-targeting and pH/redox-responsive multi-layered nanocomplexes for smart co-delivery of doxorubicin and siRNA

L Han, C Tang, C Yin - Biomaterials, 2015‏ - Elsevier
Multi-layered nanocomplexes (MLNs) were designed here to provide smart co-delivery of
doxorubicin (DOX) and vascular endothelial growth factor (VEGF) siRNA. The …